The lymphatic fluid originates from the interstitial fluid which bathes every parenchymal organ and reflects the "omic" composition of the tissue from which it originates in its physiological or pathological signature. Several recent proteomic analyses have mapped the proteome-degradome and peptidome of this immunologically relevant fluid pointing to the lymph as an important source of tissue-d...

The cerebrospinal fluid (CSF) occupies the brain's ventricles and subarachnoid space and, together with the interstitial fluid (ISF), forms a continuous fluidic network that bathes all cells of the central nervous system (CNS). As such, the CSF is well positioned to actively distribute neuromodulators to neural circuits in vivo via volume transmission. Recent in vitro experimental work in brain...

Fluorescein is modified to bear 18F so that it can act as both a positron emitter, and a fluorophore, allowing detection by positron emission tomography (PET), scintillation, and fluorescent imaging (FL). [18F]-2 is injected into the intrathecal space of rats and used to observe the cerebrospinal fluid (CSF) that bathes the brain and spine. Injury in three different applications is visualized w...

There have been important changes in the United Kingdom’s (UK) fertility and immigration in the past decade, with a large share contributed by migrants from Poland. A detailed understanding of Polish migrant fertility is lacking, however, because the relevant data are not routinely collected. This paper provides new insights into the fertility patterns of Polish migrants in the UK, and compares...

In this survey, 187 samples collected from 9 different sources of water in Tehran such as: water cool‌ers, neonates incubators, water bathes (37° C), little pools in parks or squares, cooling towers, hot or cold water taps, were examined for Legionnaires' disease agents. Inoculating water samples on selec‌tive and nonselective media resulted in isolation of several strains of gram negative bact...

This study aims to describe non-verbal semiotics and its relation Roland Barthes' semiotics, namely connotation denotation. research with the object of music video "Azza" by Rhoma Irama uses qualitative methods find contained in study. The results this study, Irama, there are seven body signs, (a) signals; (b) facial expressions; (c) eye contact; (d) language; (e) touch; (f) cue; (g) dance. It ...

Saline nasal irrigation is an adjunctive therapy for upper respiratory conditions that bathes the nasal cavity with spray or liquid saline. Nasal irrigation with liquid saline is used to manage symptoms associated with chronic rhinosinusitis. Less conclusive evidence supports the use of spray and liquid saline nasal irrigation to manage symptoms of mild to moderate allergic rhinitis and acute u...

Introduction MD is a bedside in vivo sampling technique that permits continuous analysis of a patient’s interstitial fluid chemistry. As the interstitial fluid bathes the cells, its composition reflects the local metabolic activity of those cells thus reflecting intracellular metabolic changes and disorders. The primary substances that provide information about metabolism are lactate, pyruvate,...