Notch is a key signaling protein mediating cell-fate decisions during development. In this issue, Acar et al. (2008) describe a new gene called rumi that is required for Notch signaling in Drosophila. This gene encodes an O-glucosyltransferase that attaches glucose sugars to serine residues in the multiple EGF domains of the extracellular region of Notch. This modification by Rumi likely influe...

The aim of this research is to elaborate Rumi's metaphorical disclosure in one his works, entitled Fihi Ma Fihi. complexity diction literary work can characterize as imagery, specifically metaphor. Jalal Al-Din Rumi was distinguished by works containing exquisite language, the unlikeness figurative language and placing him Persian Poet Top Seller America 1997. Therefore, utilize theoretical cri...

Mutations in Drosophila rumi result in a temperature-sensitive loss of Notch signaling. Rumi is a protein O-glucosyltransferase that adds glucose to EGF repeats with a C-X-S-X-P-C consensus sequence. Eighteen of the 36 EGF repeats in the Drosophila Notch receptor contain the consensus O-glucosylation motif. However, the contribution of individual O-glucose residues on Notch to the regulation of...

From its first introduction in this same conference, the original prototype of the Semantic Bookmarking tool Semantic Turkey has undergone a deep and extensive revision process, breaking the boundaries of its original intents and going more and more towards an extensible platform for Knowledge Management and Acquisition based on Semantic Web technologies. Following its recent official release, ...

[1] Here we describe, test, and apply a spatially explicit, global model for predicting dissolved inorganic nitrogen (DIN) export by rivers to coastal waters (NEWS-DIN). NEWS-DIN was developed as part of an internally consistent suite of global nutrient export models. Modeled and measured DIN export values agree well (calibration R = 0.79), and NEWS-DIN is relatively free of bias. NEWS-DIN pred...