Ethyl esters of omega-3 fatty acids are active pharmaceutical ingredients used for the reduction in triglycerides treatment hyperlipidemia. Herein, an ultrasonic packed-bed bioreactor was developed continuous production docosahexaenoic acid (DHA) and eicosapentaenoic (EPA) ethyl from DHA+EPA concentrate acetate (EA) using immobilized lipase, Novozym® 435, as a biocatalyst. A three-level–two-fac...

An enzyme system from Datura innoxia roots oxidizing formylphenylacetic acid ethyl ester was purified 38-fold by conventional methods such as (NH4)2SO4 fractionation, negative adsorption on alumina Cy gel and chromatography on DEAE-cellulose. The purified enzyme was shown to catalyse the stoicheiometric oxidation of formylphenylacetic acid ethyl ester to benzoylformic acid ethyl ester and formi...

Apolipoprotein (apo) E-deficient mice were fed an atherogenic diet with either 1% ethyl ester docosahexaenoic acid (DHA) or safflower oil (SO) as a source of linoleic acid for 8 week. Both genders fed DHA had higher proportions of eicosapentaenoic acid and DHA, and lower proportions of linoleic and arachidonic acids in the liver and serum phospholipids than those fed SO. Males fed DHA had great...

Volatile esters are responsible for the fruity character of fermented beverages and thus constitute a vital group of aromatic compounds in beer and wine. Many fermentation parameters are known to affect volatile ester production. In order to obtain insight into the production of ethyl esters during fermentation, we investigated the influence of several fermentation variables. A higher level of ...

The use of nicotinic acid derivatives in the field of medicinal, biomedical industries, production of cosmetics, pesticides, agro chemical industries and its biological activities have been studied extensively over the past decades. In this chapter, one of such nicotinic acid derivative called Nicotinic Acid Ethyl Ester (also known ethyl nicotinate, Ethyl 3-pyridinecarboxylate and 3-pyridinecar...

Generalized peroxisomal disorders are severe congenital diseases that involve the central nervous system, leading to severe psychomotor retardation, retinopathy, liver disease, and early death. In these disorders, peroxisomes are not normally formed and their enzymes are deficient. Characteristically, plasmalogen synthesis and beta-oxidation of very-long-chain fatty acids (VLCFAs) are affected....

3-Carbamoylmethyl-Indole-1-Carboxylic Acid Ethyl Ester (an ethoxycarbonyl derivative of indole-3-acetamide) is obtained by Friedel–Crafts type cyclocondensation γ-functionalized acetoacetamide in neat polyphosphoric acid.