Surface topography of medical implants provides an important biophysical cue on guiding cellular functions at the cell-implant interface. However, few techniques are available to produce polymeric coatings with controlled microtopographies onto surgical implants, especially onto implant devices of small dimension and with complex structures such as drug-eluting stents. Therefore, the main objec...

A facile method, i.e., nonsolvent assisted electrospraying, is proposed to fabricate hierarchically porous microspheres. The pore size on the microsphere surface ranges from a few tens to several hundred nanometers. Thermally and nonsolvent induced phase separation as well as breath figure is responsible for the formation of the hierarchical structures with different nano-sized pores. The nonso...

Nonperturbing and simple transfection methods are important for modern techniques used in biotechnology. Recently, we reported that electrospraying can be applied to DNA transfection in cell lines, bacteria, and chicken embryos. However, the transfection efficiency was only about 2%. To improve the transfection rate, physical properties of the sprayed droplets were studied in different variatio...

In this work, two different technologies (electrospraying and nanospray drying) were evaluated for the encapsulation of folic acid using both a whey protein concentrate (WPC) matrix and a commercial resistant starch. The morphology of the capsules, molecular organization of the matrices upon encapsulation, encapsulation efficiency, and stability of the folic acid within the capsules under diffe...

Electron and ion accumulation atop liquid can lead to formation of macroscopic charged hillocks electrospraying, small signal suppression by crust. Design changes for large detectors are required.

Objective(s): Encapsulated pharmaceuticals are presently the object of comprehensive investigations in many research centers due to their increased therapeutic efficiency, bioavailability, and high dissolution rate. There are different procedures for encapsulation and choice of procedure influences the size of particles for intended applications. Methods:...

Due to the low separation efficiency and poor stability, traditional polymer filtration membranes are prone be polluted difficult reuse in harsh environments. Herein, we reported a nanofibrous membrane with honeycomb–like pore structure, which was prepared by electrospinning electrospraying. During electrospraying process, addition of polydimethylsiloxane fumed SiO2 formed pores electrostatic r...

This communication describes a single-step electrospraying technique that generates core-shell microspheres (CSMs) with encapsulated protein as the core and an amphiphilic biodegradable polymer as the shell. The protein release profiles of the electrosprayed CSMs showed steady release kinetics over 3 weeks without a significant initial burst.