نتایج جستجو برای: emt

تعداد نتایج: 8534  

Journal: :Physics Letters B 2021

We discuss a puzzle in relativistic spin hydrodynamics; the previous formulation source from antisymmetric part of canonical energy-momentum tensor (EMT) is crucial. The Belinfante improved EMT pseudo-gauge transformed and usually physically sensible choice especially when gauge fields are coupled as magnetohydrodynamics, but has no part. find that pseudo-transformed entropy currents inequivale...

Journal: :Cancer Nanotechnology 2021

Abstract Background The role of epithelial–mesenchymal transition (EMT) involved in breast cancer metastasis and chemoresistance has been increasingly recognized. However, it is necessary to search for more effective strategies inhibit EMT thereby increase the sensitivity cells chemotherapy drugs. Emodin a potential overcoming tumor drug resistance restraining development EMT, but poor internal...

Background and Objective: Mesenchymal stem cells (MSCs) promote metastasis in colorectal cancer; however, the mechanism underlying this process is not fully understood. Epithelial to mesenchymal transition (EMT) is a key step in tumor acquisition of metastatic phenotype. We aimed to investigate the effect of MSCs on the expression of EMT markers, as well as cancer stem cell markers in HT-29 col...

Journal: :Veterinarni Medicina 2023

Apocrine cystomatosis, also called epitrichial sweat gland is a non-neoplastic condition characterised by multiple dilated cysts of origin. Histopathologically, these comprise two layers cells: an inner layer glandular epithelial cells and outer myoepithelial cells. A case apocrine cystomatosis was admitted to local hospital. The microscopic investigation revealed that some enlarged show...

2010
Hwajin Son Aree Moon

Epithelial-mesenchymal transition (EMT) is a complex process in which epithelial cells acquire the characteristics of invasive mesenchymal cells. EMT has been implicated in cancer progression and metastasis as well as the formation of many tissues and organs during development. Epithelial cells undergoing EMT lose cell-cell adhesion structures and polarity, and rearrange their cytoskeletons. Se...

Journal: :Journal of immunology 1998
Y Lu B Cuevas S Gibson H Khan R LaPushin J Imboden G B Mills

Ligation of the TCR or CD28 induces activation of phosphatidylinositol 3-kinase (PI3K), the TEC family protein tyrosine kinase, EMT/ITK/TSK (EMT), and the SRC family tyrosine kinase, LCK. LCK is required for the activation and phosphorylation of EMT induced by ligation of the TCR or CD28 placing LCK upstream of EMT in T cell signaling cascades. We report herein that inhibition of PI3K activity ...

Journal: :The Journal of clinical investigation 2016
Anitha K Shenoy Yue Jin Huacheng Luo Ming Tang Christine Pampo Rong Shao Dietmar W Siemann Lizi Wu Coy D Heldermon Brian K Law Lung-Ji Chang Jianrong Lu

Carcinoma cells can acquire increased motility and invasiveness through epithelial-to-mesenchymal transition (EMT). However, the significance of EMT in cancer metastasis has been controversial, and the exact fates and functions of EMT cancer cells in vivo remain inadequately understood. Here, we tracked epithelial cancer cells that underwent inducible or spontaneous EMT in various tumor transpl...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2016
Milena P Mak Pan Tong Lixia Diao Robert J Cardnell Don L Gibbons William N William Ferdinandos Skoulidis Edwin R Parra Jaime Rodriguez-Canales Ignacio I Wistuba John V Heymach John N Weinstein Kevin R Coombes Jing Wang Lauren Averett Byers

PURPOSE We previously demonstrated the association between epithelial-to-mesenchymal transition (EMT) and drug response in lung cancer using an EMT signature derived in cancer cell lines. Given the contribution of tumor microenvironments to EMT, we extended our investigation of EMT to patient tumors from 11 cancer types to develop a pan-cancer EMT signature. EXPERIMENTAL DESIGN Using the pan-...

Journal: :Laplace 2023

Jurnal ini bertujuan untuk mengetahui apa itu eurel math tollbox(EMT), tujuan dan fungsi aplikasi EMT tersebut serta penggunaan dalam pembelajaran matematika. Metode penelitian yang digunakan jurnal adalah metode ekperimen. Penelitian mengunakan eksperiment,alasan penulis menggunakan eksperimen memudahkan mahasiswa menemukan jawaban atau persoalan di hadapi dengan EMT, subjek mahasiswa/mahasisw...

2008
Michael Zeisberg Raghu Kalluri

1. Abstract 2. Introduction 3. EMT involving renal tubular epithelial cells in vitro 4. Evidence for contribution of EMT to fibrosis in experimental models of chronic kidney disease 5. Evidence for contribution of EMT to progression of chronic kidney disease in humans 6. Mediators of EMT 6.1. Transforming growth factor-β 6.2. Proteases 6.3. Integrin-linked kinase 6.4. Hypoxia 6.5 Snail 7. Exper...

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