aims: bottled water is widely used in many countries and more than 100 different brands of bottled water are produced in iran. the aim of the present research was to assess the chemical compound of some iranian brands of bottled water and compare them with the mention information on their labels.     instrument & methods: this descriptive study was performed during march to december 2012 on the...

tacrolimus, a cornerstone of immunosuppressive therapy in solid organ transplantation, has a narrow therapeutic range with considerable inter-individual and intra-individual pharmacokinetic variability. to date, there is no information on the pharmacokinetics of tacrolimus in iranian liver transplant recipients. this study was designed to determine pharmacokinetic properties of orally administe...

The complexes between C20 and C2 X4 , C2 X2 (X = H, F, Cl, Br) have been studied theoretically at the B3LYP/6-311G (d,p) level. The calculations include the optimized geometries, the interaction energies, aromaticity and thermodynamic. The interaction energies ranging from -60 to -101 kcal/mol and being ordered as: X = F> Cl > Br. Natural bond orbital (NBO) analysis has been performed on all ge...

Tetryzoline(TH) is an adrenergic agent (vasoconstrictors) and derived from imidazoline. This compound is closely related to naphazoline hydrochloride in its pharmacological action. Nanotechnology has been used to provide advanced biomedical research tools in drug delivery. The fullerene family especially C60 derivatives have appealing photo-, electro-chemical and physical properties for biomedi...

When the dividing cells can be assumed to be in a random phase of the cell cycle, the cell cycle length is constant and the population does not increase in size during the exposure time, the fraction labelled cells (F) is determined by the exposure time and the unknown lengths of the S-phase and the cell cycle [1,2]. When two different exposure times are used, the unknown lengths can be derived...

Many bacterial species protect themselves against environmental F(-) toxicity by exporting this anion from the cytoplasm via CLC(F) F(-)/H(+) antiporters, a subclass of CLC superfamily anion transporters. Strong F(-) over Cl(-) selectivity is biologically essential for these membrane proteins because Cl(-) is orders of magnitude more abundant in the biosphere than F(-). Sequence comparisons rev...

2-Chloro-9-(2'-deoxy-2'-fluoro-beta-d-arabinofuranosyl)adenine (Cl-F-ara-A, clofarabine), a purine nucleoside analog with structural similarity to 2-chloro-2'-deoxyadenosine (Cl-dAdo, cladribine) and 9-beta-d-arabinofuranosyl-2-fluoroadenine (F-ara-A, fludarabine), has activity in adult and pediatric leukemias. Mediated transport of the purine nucleoside analogs is believed to occur through the...

1,2-Dichloro-3,3,4,4,5,5-hexafluorocyclopentene (F 6 cypCl 2 ) was functionalized with diphenyl- and dimesitylphosphanyl groups by a salt-elimination reaction of the respecttive chlorophosphane (PPh Cl, PMes Cl) in situ generated lithiated F cyp(Li)Cl. cyp(PR )Cl (R = Ph, Mes) functionalised again to obtain corresponding trimethylstannyl substituted compounds )(SnMe 3 Mes). These tin-precursors...

DFT calculations were used to investigate adsorptionof  F-, Cl-, Li+ and Na+ ions on the exterior surface of Mg12O12 nanocage in the gas phase and water media. The most favorite position for adsorption of the studied anions and cations are atop of Mg and O atoms of Mg12O12, respectively. The strongest intera...