Introduction More than one-thousand trials with functional magnetic resonance imaging (fMRI) as an outcome measure were registered in clinicaltrials.gov at the time of writing this article. However, 93% these are still not completed published results and there is no picture available about methodological dimensions ongoing fMRI measure. Methods We collected that use ClinicalTrials.gov registry ...

Elucidating the brain regions and networks associated with cognitive processes has been mainstay of task-based fMRI, under assumption that BOLD signals are uncompromised by vascular function. This is despite plethora research highlighting modulations due to changes induced disease, drugs, aging. On other hand, fMRI-based assessment cerebrovascular reactivity (CVR) often used as an indicator bra...

Functional Magnetic Resonance Imaging (fMRI) is an essential tool for the pre-surgical planning of brain tumor removal, which allows identification functional networks to preserve patient’s neurological functions. One fMRI technique used identify network resting-state-fMRI (rs-fMRI). This not routinely available because necessity have expert reviewer who can manually each network. The lack suff...

Electroconvulsive therapy (ECT) is one of the most effective treatments for major depressive disorder (MDD). Biomarkers predicting individuals’ response to ECT would provide more successful and personalized treatment strategies. This study aimed investigate whether dynamic functional connectivity (dFC) estimated from resting-state fMRI (rs-fMRI) predicts outcome.

  ABSTRACT  Background: The brain response to temporal frequencies (TF) has been already reported, but with no study reported for different TF with respect to various spatial frequencies (SF).  Materials and Methods: fMRI was performed by 1.5T GE-system in 14 volunteers during checkerboard, with TFs of 4, 6, 8 and 10Hz in low and high SFs of 0.5 and 8cpd.  Results: Average percentage BOLD signa...

Pre-operative determination of the dominant hemisphere for speech and speech associated sensory and motor regions has been of great interest for the neurological surgeons. This dilemma has been of at most importance, but difficult to achieve, requiring either invasive (Wada test) or non-invasive methods (Brain Mapping). In the present study we have employed functional Magnetic Resonance Imaging...

Introduction: Multiple Sclerosis (MS) is the most common non-traumatic neurological diseases of young adults. MS often reported during ages 20-62. MS affects the various anatomical parts of the central nervous system. Up to 65% of multiple sclerosis patients MS patients suffer from various problems, such as fatigue, depression, pain and sleep disorders. Unlike MRI, that only sh...

introduction as functional magnetic resonance imaging (fmri) is too expensive and time consuming, its frequent implementation is difficult. the aim of this study is to evaluate repeatability of detecting visual cortex activity in fmri. materials and methods in this study, 15 normal volunteers (10 female, 5 male; mean age±sd: 24.7±3.8 years) attended. functional magnetic resonance images were ob...

Introduction: Prior studies comparing Hemodynamic Response Function (HRF) in the young and elderly adults based on fMRI data have reported inconsistent findings for brain vision and motor regions in healthy aging. It is shown that the averaging method employed in all previous works has caused this inconsistency. The averaging is so sensitive to outliers and noise. However, fMRI data are o...