Allene chemistry has attracted considerable attention in recent years. In particular, the transition-metal-catalyzed reaction of allene derivatives bearing an a substituent, such as hydroxy, carbonyl, carboxy, thio (sulfanyl), and amino groups, has led to many synthetically useful transformations. 2] One important reaction among them is the transition-metal-catalyzed cyclization of allenyl keto...

Abstract A facile, efficient, and metal-free single-flask procedure for the synthesis of trisubstituted furans from simple readily available homopropargylic alcohols is described. combination Dess–Martin periodinane, H2O, TsOH·H2O plays a crucial role in formation furans. The advantages this method include operational ease, mild reaction conditions, good functional-group tolerance.

transforming relatively complex starting materials into substituted heterocycles, and for the functionalization of existing heterocycles, there is less precedent for methodology which involves the direct, regiodefined synthesis of highly substituted heterocycles from simple starting materials. As such, new methods for the synthesis of substituted heterocycles (or their precursors) are potential...

Enantiomerically pure 2-substituted-2,5-dihydro-3-(aryl) sulfonyl/sulfinyl furans have been prepared from the easily accessible carbohydrate derivatives. The orientation of the substituents attached at the C-2 position of furans is sufficient to control the diastereoselectivity of the addition of various nucleophiles to the vinyl sulfone/sulfoxide-modified tetrahydrofurans, irrespective of the ...

A convenient base-mediated strategy to synthesize 3-aryol-4-methyl (or benzyl)-2-methylthio furans 2 (trisubstituted furans) has been developed through the domino coupling/annulations between available α-oxo ketene dithioacetals 1 and propargyl alcohols. In this strategy, these types of bases play an important role in driving the domino coupling reaction of propargyl alcohols and further intram...

In this paper the polychlorinated-dibenzo dioxins and furans (PCDD/Fs) release is analyzed during an hydrothermal carbonization process of the organic fraction of municipal solid waste (OFMSW). Two models to estimate the quantity of PCDD/Fs that can be released during this kind of process are presented in this paper. The first model follows a mass balance approach; the second one develops a phe...

Tetrasubstituted furans were efficiently synthesized from Fe(OAc)2-catalyzed C-H/C-H cross-dehydrogenative-coupling (CDC) reactions of activated carbonyl methylenes with S,S-functionalized internal olefins, that is, α-oxo ketene dithioacetals and analogues, under oxidative conditions. β-Ketoesters, 1,3-dicarbonyls, β-keto nitrile, and amide derivatives were used as the coupling partners. The re...