نتایج جستجو برای: g1 epitope

تعداد نتایج: 45035  

Journal: :iranian journal of applied animal science 2015
s. yousefi m. tahmoorespur m.h. sekhavati

brucellosis, produced by brucella species, is a disease that causes severe economic losses for livestock farms worldwide due to serious economic and medical consequences of this disease, many efforts have been made to prevent the infection through the use of recombinant vaccines based on brucella outer membrane protein (omp) antigens. in the present study, a wide range of on-line prediction sof...

Journal: :BMC Musculoskeletal Disorders 2008
Jean C Rousseau Eren U Sumer Gert Hein Bodil C Sondergaard Suzi H Madsen Christian Pedersen Thomas Neumann Andreas Mueller Per Qvist Pierre Delmas Morten A Karsdal

BACKGROUND Rheumatoid arthritis (RA) is a chronic auto-immune disease with extensive articular cartilage destruction. Aggrecan depletion, mediated by aggrecanases is one of the first signs of early cartilage erosion. We investigated, whether measurement of aggrecan and fragments thereof in serum, could be used as biomarkers for joint-disease in RA patients and furthermore characterized the frag...

Background and purpose: In 2019, the world has witnessed the emergence of a virus that caused acute respiratory distress syndrome in human with high mortality rates (approximately 3.7%). So far, no effective treatment has been proven against COVID-19. This study aimed at designing a multi-epitope vaccine combining several T-cell and B-cell epitopes of the SARS-CoV-2. Materials and methods: Bas...

Journal: :Clinical and experimental immunology 2013
M Chéramy C S Hampe J Ludvigsson R Casas

Previous studies have indicated phenotypical differences in glutamic acid decarboxylase 65 autoantibodies (GADA) found in type 1 diabetes (T1D) patients, individuals at risk of developing T1D and stiff-person syndrome (SPS) patients. In a Phase II trial using aluminium-formulated GAD(65) (GAD-alum) as an immunomodulator in T1D, several patients responded with high GADA titres after treatment, ...

زیبایی, سعید, حق‌پرست, ، علیرضا , دوستی, محمد , طهمورث‌پور, مجتبی , نصیری, ، محمدرضا ,

     Foot-and-mouth disease (FMD) is an extremely infectious and occasionally fatal viral disease with a rapid onset and a short course that affects cloven-hoofed animals and results in considerable financial losses. For this reason, availability of more reliable and efficient vaccines against Foot-and-mouth disease virus (FMDV) is felt as a necessity. The purpose of this study is to develop a ...

Journal: :The Plant cell 2004
Olga A Koroleva Matthew Tomlinson Piyarat Parinyapong Lali Sakvarelidze David Leader Peter Shaw John H Doonan

A putative G1 cyclin gene, Antma;CycD1;1 (CycD1), from Antirrhinum majus is known to be expressed throughout the cell cycle in the meristem and other actively proliferating cells. To test its role in cell cycle progression, we examined the effect of CycD1 expression in the tobacco (Nicotiana tabacum) cell suspension culture BY-2. Green fluorescent protein:CycD1 is located in the nucleus through...

Journal: :iranian journal of biotechnology 2008
malihe nazari jahantigh kamran ghaedi mohamad hossein nasr isfahani somayeh tanhaei farzaneh rabiee

epitope tagging is a method of expressing proteins whereby an epitope for a specific monoclonal antibody is fused to a target protein using recombinant dna techniques. the aim of this study was to sub-clone the peroxisomal protein (pep) cdna into a mammalian expression vector leading to the formation of a  chimeric pep-cdna containing the flag epitope. the flag-pep recombinant cdna was construc...

Farzaneh Rabiee Hossein Baharvand Kamran Ghaedi Khadijeh Karbalaei Malihe Nazari Jahantigh Maryam Ostad Sharif Marzieh Nematollahi Mehran Miroliaei Mohamad Hossein Nasr Isfahani Shahnaz Razavi Somayeh Tanhaei

Epitope tagging is a method of expressing proteins whereby an epitope for a specific monoclonal antibody is fused to a target protein using recombinant DNA techniques. The aim of this study was to sub-clone the peroxisomal protein (PEP) cDNA into a mammalian expression vector leading to the formation of a  chimeric PEP-cDNA containing the FLAG epitope. The FLAG-PEP recombinant cDNA was construc...

2003
Karin Fijnvandraat Wendy S. Bril Jan Voorberg

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