Ependymomas accounts for about 2%–6% of CNS and 60%–70% of spinal cord tumors. Several histological patterns of these neoplasms are well known, but little attention has been devoted to a variant composed of giant cells. In spite of apparently “worrisome” histology, giant cell ependymoma seems to be a neoplasm with a relatively good prognosis. This report presents a case of giant cell ependym...

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aplasia cutis congenita is a rare anomaly presenting with the absence of skin. no definite etiology is available. the most common site is the scalp. we present an instance with acc occurring symmetrically in both sides of the body from chest to flank.

giant cell fibroma (gcf) was described as a new entity of fibrous hyperplastic soft tissue. it seems that stimulus from an unexplained origin can have a role in its etiology. histopathologically gcf is consisted of multinucleated fibroblasts that have oval shape nuclei within the eosinophilic cytoplasm. surgical excision is the treatment of choice and recurrence is very rare. here we report a c...

Giant cell glioblastoma is an extremely rare variant of Glioblastoma (WHO grade IV) which is characterized by a predominance of bizarre, multinucleated giant cells. These tumors comprise of 0.8% of brain tumors and up to 5% of glioblastomas. In pediatric age group, these tumors are still uncommon with only around 53 published cases since 1952. Here, we report a case of a 12-year old female pat...

the aim of this article is to present a new technique of giant omphaloceles repair in neonatal period and also later in life in patients that the primary repair has been failed. from 1999 to 2006, seven consecutive children (male/female ratio 0.4) with giant omphalocele (n=6) and gastroschesis (n=2) were underwent this new operation in our center. in this technique, there were two operations. t...

background: giant cell tumor is a benign but locally aggressive bone neoplasm which uncommonly involves the skull. giant cell tumor (gct) of the sphenoid bone is relatively rare. in this report, we describe a tumor of the greater wing of left sphenoid bone. case presentation: a 31-year-old female was presented with headache, proptosis and diplopia of her left eye. cranial magnetic resonance ima...

introduction: central giant cell granuloma is a benign lesion but sometimes has aggressive proliferation composed of multinucleated giant cells in a background of spindle and ovoid mesenchymal cells. multifocal central giant cell granuloma of jaws is very rare and usually associated with hyperparathyroidism and some syndromes. we described an un-usual case of a 22-year-old man with idi-opathic ...

central giant cell granuloma is a benign, aggressive neoplasm composed of multinucleated giant cells that almost exclusively occurs in the jaws though extra-gnathic incidence is rare.multifocal cgcgs of the jaws are very rare and suggestive of systemic diseases such as hyperparathyroidism,an inherited syndrome such as noonan-like multiple giant cell lesion syndrome or other disorders.very few c...

Background: Giant cell tumor is a benign but locally aggressive bone neoplasm which uncommonly involves the skull. Giant cell tumor (GCT) of the sphenoid bone is relatively rare. In this report, we describe a tumor of the greater wing of left sphenoid bone. Case presentation: A 31-year-old female was presented with headache, proptosis and diplopia of her left eye. Cranial magnetic resonance ima...