Acanthamoeba keratitis (AK) is a sight-threatening infection of the cornea disease that often presents with a lengthy and not fully effective treatment. Current therapeutic options against Acanthamoeba are not very effective against the cyst. Calibrated trophozoite/cyst suspension was incubated with the same volume of serial dilutions of the Trigonella foenum graecum aqueous extract (200, 250, ...

The objective of the study was to search for the appropriate herbal extracts by comparative analysis of their estrogenic and cytotoxic activities. Some potentially estrogenic activity of herbal extracts in the management of female disorder symptoms was investigated by E-screen assay. The extracts having a promising activity were further evaluated in vitro for their cytotoxic activity. Of 13 her...

Objective- Trigonella foenum graecum, (Fenugreek) has anti-inflammation, antiseptic and antidiabetic activities in traditional medicine. This study was performed to investigate the protection effects of Fenugreek seed extract on the experimental reflux esophigitis (RE) in rats. Design- experimental study. Animals- 24 male Wistar albino rats. Procedures- Rats were randomly allocated into 4 group...

The aim of the study was to investigate distribution, enrichment and accumulation of heavy metals in soil and Trigonella foenum-graecum (var. Pusa Early Bunching) after fertigation with paper mill effluent. Doses of paper mill effluent viz. 5%, 10%, 25%, 50%, 75% and 100% were used for fertigation of T. foenum-graecum along with bore well water (control). The results revealed that paper mill ef...

The alarming increase in bacterial resistance to antibiotics caused some authors state that we are approaching a post-antibiotic era and medical catastrophe, the study aimed assess antimicrobial effects of selected plant extracts against several sensitive resistant isolates. Experimental cross-sectional was conducted, 70% ethanol crude Acaccia nilotica, Trigonella foenum-graecum, Punica granatu...

To separate the saponin rich fraction of Trigonella foenum graecum (TFG) seeds and to evaluate its influence on blood pressure in normal and hypertensive rats. The ethanolic extract of TFG seeds was fractionated with cold diethyl ether to obtain saponin rich fraction. Albino rats of Wistar strain of either sex weighing between 200 to 250 g were used for the hypertension models. Hypertension was...

Trigonella foenum-graecum (fenugreek) seeds have been documented as a traditional plant treatment for diabetes. In the present study, the antidiabetic properties of a soluble dietary fibre (SDF) fraction of T. foenum-graecum were evaluated. Administration of SDF fraction (0 x 5 g/kg body weight) to normal, type 1 or type 2 diabetic rats significantly improved oral glucose tolerance. Total remai...