ADAM metalloprotease-disintegrins share a common modular structure of functional domains for proteolytic, cell adhesion, and signaling interactions. The metalloprotease domain of oughly half of the known ADAMs contain an intact consensus metzincin catalytic site, and they are thus thought to function as active metalloproteases. The types of interactions mediated by ADAMs are expressly conspicu...

Background: Microparticles (MPs) are small vesicles released from the cell membrane. Accordingly, these contain active molecules to mediate biological processes, including cell proliferation and cell cycle progression. The fusion of myeloma cell lines with immunized B lymphocytes is a critical step of hybridoma technology. MPs modulate lymphoproliferation, thereby facilitating B cell expansion ...

background: ß-carbolines, harmaline and harmine, are the major alkaloids presenting in the seeds of the peganum harmala l. these alkaloids are known as herbal active principals with potential use in pharmaceutical and medicine. objectives: to assess the growth inhibitory effect of phyto-alkaloids, harmaline and harmine, on cancer cell lines. methods: the p. harmala l.’s alkaloids were extracted...

In this study, the effect of cement content on concrete performance in corrosive environments is investigated on concrete mixtures having the same water/cement (w/c) ratio. Three w/c ratios (0.40, 0.45 and 0.50) were used and for each w/c ratio three mixtures were prepared with cement contents 350, 400 and 450 kg/m3. The compressive strength, electrical resistivity and chloride diffusivity of t...

Titanium and fluoride-containing hydroxyl apatite were synthesized through precipitation method following by a hydrothermal stage at 100oC for 6 hours. XRD analysis of the sample scalcinedat650oC for 1 hour revealed that all samples have pure apatite structure. The existence of Fluoride substitution in apatite structure was confirmed by FTIR(Fourier Transform Infrared Spectroscopy) analysis. Su...