the main role of cumulus cells (cc) is to provide nutritious materials for developing oocytes. follicular fluid (ff) contains the enzyme acid phosphatase, which plays a role in ovulation and fertilization of oocyte. the objective of this prospective study was to evaluate the levels of acid phosphatase in ff and the rate of apoptosis in cc of fertilized and unfertilized oocytes in intracytoplasm...

background: nano-particles are extensively employed in most industries. several studies have been started to explore the probable detrimental effects of nano-particles on human reproduction. however, there is insufficient and controversially evident of effects of silver nano-particles on sperm parameters and other reproductive indices. objective: investigation of the effects of silver nano-part...

introduction: transplantation of germ cells restores the male fertility. nevertheless, a lot of questions remain incompletely resolved. the aim of this study was to evaluate in vitro colonization efficiency of germ cells and sperm production capacity of spermatogonial cells before and after culture by sperm number assay in epididymis of recipient mice. materials and methods: we developed a sert...

sperm cells are one of the most stellar and fas-cinating cells in all species. one of the most distinctive characteristic of these cells is their movement dynamics which can be observed through a light microscope. the first paper regarding sperm cell biology that appeared on pubmed was pres-ented by dr. w.f. whitney (1). there, he showed the staining properties of spermatozoa and it was publish...

BACKGROUND The existence of a genetic component to human infertility has been suggested, although neither the specific abnormalities involved, nor their genetic mechanism of transmission, are currently defined. We have examined, by transmission electron microscopy (TEM), ejaculate from 1600 males with fertility problems. Among the subjects studied, we focused on a group of patients whose family...

the objective of this study was to review the literature on sperm transport in the mare. during this process the sperm cells must reach the oviducts in order to fertilize the oocyte, but before reaching this site it must go through the uterus that is a hostile environment at this moment since there is an inflammatory reaction in this location that aims to eliminate excess spermatozoa and bacter...

Sperm-specific natural selection Sperm cells are genetically haploid, but because of the cytoplasmic bridges that link cells, they can be transcriptionally diploid. However, some gene transcripts not shared. Bhutani et al. sequenced single sperm from mice, cattle, and macaques to determine extent distortion in expression these putatively selfish transcripts, which authors call genoinformative m...

STUDY QUESTION Does the application of three different artificial activating stimuli lead to a difference in pre- and post-implantation embryo development in the wobbler mouse, a mouse model with oocyte activation deficient round-headed sperm cells similar to human globozoospermia? SUMMARY ANSWER No gross differences were found between strontium chloride, electrical pulses or ionomycin with r...

introduction: in the present investigation, we aimed to study the effect of different concentrations of ascorbate/vitamin c, on membrane integrity, viability, and acrosome reaction of human spermatozoa in presence of ferrous (fe2+) ions as lipid peroxidation (lpo) promoter. material and methods: we used 12 semen samples from healthy donors in shahrekord. the samples were then washed twice with ...

Background: Male infertility is a widespread problem and increased number of mast cells-induced by some drugs like sulpiride atipycal antipsychotic drug, ara described in the testis of males, exhibiting impaired sper-matogenesis and fertility disorders. In this study number of mast cells and sertoli cells, thickness of seminiferous tubule’s lamina propria and sperm concentration and viability i...