BACKGROUND Diabetes, obesity, and the metabolic syndrome are multifactorial diseases dependent on a complex interaction of host genetics, diet, and other environmental factors. Increasing evidence places gut microbiota as important modulators of the crosstalk between diet and development of obesity and metabolic dysfunction. In addition, host genetics can have important impact on the compositio...

Mammals exhibit marked interindividual variations in their gut microbiota, but it remains unclear if this is primarily driven by host genetics or by extrinsic factors like dietary intake. To address this, we examined the effect of dietary perturbations on the gut microbiota of five inbred mouse strains, mice deficient for genes relevant to host-microbial interactions (MyD88(-/-), NOD2(-/-), ob/...

Abstract Cyanobacteria periodically dominate phytoplankton composition in lakes, and produce a wide array of toxic secondary metabolites. Blooms cyanobacteria often coincide with infections zooplankton by microparasites (such as Metschnikowia bicuspidata , parasitic yeast Daphnia ), prior research has shown that cyanobacteria-based diets could mitigate fungal the host. Here, we tested whether c...

We investigated the effects of high protein intake on host resistance to Paracoccidioides brasiliensis. Two-d fasted mice were infected with P. brasiliensis and refed on diets with three different levels (54%, 20%, and 5%) of casein. The mice refed the 54% casein diet showed reduced antifungal activity in the spleen and liver as compared with the mice refed the 5% or the 20% casein diet. After ...

Studies of ant biodiversity are important to understand their group better, as well extend our knowledge on the evolution associated organisms. Host-associated microbial communities, and particularly bacterial shaped by different host factors such habitat, diet, phylogeny. Here, we studied structures eukaryote communities with Amazonian ants collected from two habitats: rainforest city. We 38 s...

The human gut microbiome responds dynamically to changes in diet, contributing the diversity of diet. composition diet can also influence metabolic products that are ultimately present intestinal lumen and plasma. Observations humans on vegan, omnivorous, or synthetic enteral diets deficient fiber have demonstrated dramatic imbalances microbiome, accompanied by carbohydrate amino acid-derived b...