Background: Titanium (Ti) implants are commonly coated with hydroxyapatite (HA). However, HA has some disadvantages such as brittleness, low tensile strength and fracture toughness. It is desirable to combine the excellent mechanical properties of ZrO2 and the chemical inertness of Al2O3 with respect to the purpose of this project which was coating Ti implants with HA-ZrO2-Al2O3 to modify the s...

in this study, hydroxyapatite (ha) nanocrystals have been synthesized via chemical precipitation technique. diammonium hydrogen phosphate and calcium nitrate 4-hydrate were used as starting materials and sodium hydroxide solution was used as the agent for ph adjustment. the powder sample was evaluated by techniques such as scanning electron microscope, transmission electron microscope, fourier ...

Porous silicon (PS) substrates, with different pore sizes and morphology, have been used to crystallize hydroxyapatite (HA) nano-fibers by an easy and economical procedure using a co-precipitation method at room temperature. In situ formation of HA nanoparticles, within the meso- and macroporous silicon structure, resulted in the formation of nanometer-sized hydroxyapatite crystals on/within th...

The aim of this work was to investigate the effect of silica coating on bioactivity and biodegradability of hydroxyapatite. In this purpose, we firstly attempted to synthesis hydroxyapatite (HA) nanoparticles and its silica coated (Si-HA) sample in collagen matrix using calcium chloride, sodium phosphate and sodium silicate. Characterization of the sample was carried out using Fourier transform...

Nowadays, titanium-based alloys are among the most attractive metallic materials for biomedical applications (as implants) due to their non-biodegradability, low density, good mechanical properties as well as their good biocompatibility. Hydroxyapatite (Ca10 (PO4)6(OH)2, HA) has been widely used for biomedical applications due to its bioactive, biocompatible and osteoconductive properties. Firs...

This study compared in vivo the performances of commercially pure titanium (cp Ti) screw dental implants either uncoated or coated with synthetic hydroxyapatite (HA) by electrophoresis. The HA coating was characterized by scanning electron microscopy, energy dispersive spectroscopy (EDS) and Fourier-transform infrared (FT-IR) spectroscopy. Well-adhered carbonated-hydroxyapatite layers (4- to-8-...

The goal of this work is to identify a peptide that can specifically bind bone mineral hydroxyapatite [(Ca5(PO4)3OH)2] from a phage-displayed random peptide library. Instead of using pIII library where random peptides are displayed at the tip of filamentous phage, we used landscape phage libraries, in which random octa-peptides or nona-peptides are displayed on all the N-termini of the pVIII (m...

This study aimed to determine the guided bone regeneration (GBR) capacity of peri-implant bone defect treatment, either with only a hydroxyapatite bone graft or with a hydroxyapatite bone graft mixed with zoledronic acid (ZA) and employing polyethylene glycol (PEG) barrier membranes. In this study, four male New Zealand rabbits were used. First, the rabbits were randomly divided into two groups...

Functionally graded metal-ceramic composite was fabricated by pressure-less sintering. The pure metallic component (Ti) and the pure ceramic component (HA) were located at the ends of a cylindrical specimen. Titanium and-Hydroxyapatite were utilized as a metallic and ceramic layer. The target sample thickness was 6 mm with radius cylindrical 20 mm. The sample was made from the cylindrical type ...

BACKGROUND AND PURPOSE Plasma-sprayed hydroxyapatite (HA) is a successful coating for fixation of uncemented femoral stems. There may be alternative coatings with advantages in bone remodeling and transport of bone-active substances. We investigated whether an electrochemically deposited hydroxyapatite, Bonemaster (BM), might be a safe alternative in total hip arthroplasty. Our hypothesis was t...