Previous studies have shown that exercise can prevent white matter atrophy in APP/PS1 transgenic Alzheimer's disease (AD) mice. However, the mechanism of this protective effect remains unknown. To further understand this issue, we investigated the effects of exercise on the blood supply of white matter in transgenic AD mice. Six-month-old male APP/PS1 mice were randomly divided into a control g...

Memory-related program failures in multithreaded programs can be caused by a variety of bugs. Concurrency bugs can occur due to unexpected or incorrect thread interleavings during execution. Other kinds of memory bugs, such as buffer overflows and uninitialized reads, may also occur in multithreaded as well as single-threaded programs. Most prior techniques for isolating these bugs are speciali...

Maternal infection is an important factor causing neonatal brain injury and later developmental disability. In the present study, we investigated the effects of treadmill exercise intensity on short-term memory, hippocampal neurogenesis, and expression of brain-derived neurotrophic factor (BDNF), and tyrosine kinase receptor B (TrkB) in the rats born of lipopolysaccharide (LPS)-exposed maternal...

Hutchinson et al offer a compelling argument for greater attention to and work in corruption in healthcare. We indeed need to talk about corruption, to understand and to grasp how to prevent and address it. This paper lays out some of the rationale for how to define the research questions, how best to address corruption – arguing that governance rather than corruption may offer a preferred star...

We show that for all given n, t, w ∈ {1, 2, . . .} with n < 2, an array of n entries of w bits each can be represented on a word RAM with a word length of w bits in at most nw + dn(t/(2w))e bits of uninitialized memory to support constant-time initialization of the whole array and O(t)-time reading and writing of individual array entries. At one end of this tradeoff, we achieve initialization a...

increased level of stress has negative effects on cognitive functions. thus, it is necessary to identify appropriate strategies to prevent cognitive and motor performance decline. the aim of this research was to study the effect of immobilization stress on learning and memory and the protective role of physical activity in them. from male albino-wistar rats of pastor institute, 32 rats were ran...

Vulnerabilities in software programs made possible the widespread and frequent occurrence of malware outbreaks. Extensive research has been devoted to detection and prevention of control hijacking attacks due to their prevalence. The non-control data attacks are not yet so prevalent, but, as more and more avenues are closed for the malicious software authors they will gain

We present a study of the effects of disk and memory corruption on file system data integrity. Our analysis focuses on Sun’s ZFS, a modern commercial offering with numerous reliability mechanisms. Through careful and thorough fault injection, we show that ZFS is robust to a wide range of disk faults. We further demonstrate that ZFS is less resilient to memory corruption, which can lead to corru...

background: different stressors induce learning and memory impairment and physical activity influence learning and memory enhancement. in this research, we investigated the effect of synchronized running activity with stress on acquisition and retention time of passive avoidance test. methods: male wistar rats were randomly divided into five groups as follows: control (co), sham (sh), exercise ...