let $g$ be a simple graph with vertex set $v(g) = {v_1, v_2,ldots, v_n}$ and $d_i$ the degree of its vertex $v_i$, $i = 1, 2,cdots, n$. inspired by the randi'c matrix and the general randi'cindex of a graph, we introduce the concept of general randi'cmatrix $textbf{r}_alpha$ of $g$, which is defined by$(textbf{r}_alpha)_{i,j}=(d_id_j)^alpha$ if $v_i$ and $v_j$ areadjacent, and zero otherwise. s...

social system based on mutual trust among members continues to exist. social trust in modem era is more important than earlier periods. subject of current report is focused on the trust of iranian students in different aspects. main question in this investigation is about social-political trust of these students (based on trust in islamic republic of iran) at the past and present. this matter e...

introduction: public health is a life quality concerning a person's emotional, mental, moral states and biological fitness that helps him to be able to adapt to the surrounding environment and do sufficient amount of physical, mental, and social work. materials and methods: in this cross sectional study, 903 families from different cities of ilam were selected through multistage cluster sa...

IntroductionIn most developing countries, antimicrobial resistance is a public threat, and insufficient knowledge of antibiotics among the adds to it. This study aimed determine efficacy clinical pharmacist's pamphlets video-based educational tools address public's knowledge, attitude, practice gaps on antibiotic use.MethodsThis was pre-and post-intervention cohort adult population in South Ind...

IntroductionIn the Rituximab for Relapse Prevention in Nephrotic Syndrome (RITURNS) trial, we demonstrated superior efficacy of single-course rituximab over maintenance tacrolimus preventing relapses children with steroid dependent nephrotic syndrome (SDNS) during a 1-year observation. Here present long-term outcomes all 117 trial completers, who were followed up another 2 years.MethodsRelapsin...

Background: Tramadol is an opioid analgesic indicated for the management of moderate and severe pains. Its side effects, in parts are due to the activation of µ receptors and in parts to increasing central catecholamine and serotonin levels. In the case of long administration, tramadol has a potential to cause dependency, tolerance and also drug abuse. After prohibition of injective diclofenac,...

introduction: the e xecution of composed educational programs for general practitioners is one of the most common methods of continuing medical education. this research project aims to evaluate one of these programs. methods: for this purpose, a pre- and post-test design was developed. the subjects consisted of 45 participants. they were tested (by a 76 mcq knowledge test) in two stages: before...

IntroductionIn patients suffering from unilateral osteoarthritis in the knee, an osteotomy can provide symptomatic relief and postpone need for replacement of joint. Nevertheless, open-wedge osteotomies (OWOs) around knee joint face several challenges like postoperative pain bone nonunion.ObjectivesIn this study, aim was to design, fabricate, evaluate a gap-filling implant OWO using osteoinduct...

IntroductionIn cohort G of KEYNOTE-021 (NCT02039674), first-line pembrolizumab plus pemetrexed-carboplatin significantly improved the objective response rate and progression-free survival versus chemotherapy alone with manageable toxicity in advanced nonsquamous NSCLC. We report long-term outcomes from this study.MethodsPatients previously untreated NSCLC without sensitizing EGFR or ALK alterat...