Higher education institutions and their students face a wide range of infectious disease threats (IDTs). However, there is lack theory-driven research on how to provide communication for multiple IDTs motivate protective action taking. To close this gap, study focuses college two IDT types: respiratory sexually transmitted infections. We tested an appraisal model with data from online survey co...

The metabolic activation of a drug to an electrophilic reactive metabolite and its covalent binding to cellular macromolecules is considered to be involved in the occurrence of idiosyncratic drug toxicity (IDT). As a cellular defense system against oxidative and electrophilic stress, phase II enzymes are known to be induced through a Kelch-like ECH-associated protein 1/nuclear factor E2-related...

conclusions considering the high rates of relapse, more attention should be paid to reasons for relapse. it seems necessary that both clinical and psychological approaches would be undertaken simultaneously. background relapse prevention is a medical intervention designed for educating cognitive and behavioral skills to avoid continued drug abuse and relapse. objectives this study examined high...

Many cellular systems rely on the ability to interpret spatial heterogeneities in chemoattractant concentration to direct cell migration. The accuracy of this process is limited by stochastic fluctuations in the concentration of the external signal and in the internal signaling components. Here we use information theory to determine the optimal scheme to detect the location of an external chemo...

Betalactam (BL) antibiotics are the most common cause of drug-induced hypersensitivity reactions (DHR). We present 2 clinical cases patients with suspected immediate BL DHR who underwent drug allergy workup according to standardized diagnostic procedures, including skin tests (STs: prick, prick test, and intradermal [IDTs]) provocation (DPTs).1 ST results became positive after first DPT dose. T...