Background Asthenozoospermia accounts for almost 50% of the cases of male infertility. Our study investigating phosphoproteins differentially expressed in asthenozoosperm has identified the phosphoproteins relevant to sperm motility and the signature molecules likely to be altered in asthenozoospermia. The 66 phosphoproteins differentially expressed included four alpha tubulin isoforms which we...

Herein, we assessed the effect of full native peptide amyloid-beta (Aβ) (1-42) and its fragments (25-35 35-25) on tissue transglutaminase (TG2) isoforms (TG2-Long TG2-Short) expression levels olfactory ensheathing cells (OECs). Vimentin glial fibrillary acid protein (GFAP) were also studied. The pre-treatment with indicaxanthin from Opuntia ficus-indica fruit TG2 isoforms, cell viability, total...

human leukocyte antigen-g which is an immune tolerance effecter molecule has an important role in the maintenance of fetus during pregnancy. abortion is one of the complications of pregnancy period.  in this research, we have studied levels of hla-g 5, hla-g7 isoforms in the abortion-threatened pregnant women in comparison with controls. in a case-control study, 101 abortion-threatened women an...

Investigation of Performance and Comparison Cytochrome P450 Isoforms in Broiler Chickens Liver Fed Silver Nanoparticles Coated on Clinoptilolite

PKCδ and PKCθ are PKC isoforms that activated by diacylglycerol may be inhibited calphostin C, Gö 6983 chelerythrine.

The high lethality in peritonitis and the lack of data on role various NO-synthase isoforms its pathogenesis suggests advisability research to study effects (NOS) inhibitors.

Thioredoxins (Trxs) are small ubiquitous disulfide reductases that participate in dithiol-disulfide exchange reactions. In contrast to animals and prokaryotes that typically possess one or a few genes encoding Trxs, higher plants contain eight different Trx types: f, m, x, y, z, o, s, and h. Trx h with multiple forms is involved in different processes such as seed germination, cellular protecti...

The second messenger, cyclic adenosine monophosphate (cAMP), is a master regulator of signal transduction that maintains cell homeostasis. A fine balance between cAMP synthesis by adenylyl cyclase and degradation phosphodiesterases (PDEs) underpins receptor-specific responses. As multiple receptors rely on for signaling, PDEs shape three-dimensional, localized gradients the nucleotide to drive ...