BACKGROUND & OBJECTIVE Cerebral hypoxia is known to be involved in many neurodegenerative diseases such as Alzheimer's and cerebrovascular dementia. The present study was designed to investigate the effects of flavonoids from aerial part of Scutellaria baicalensis Georgi (SSF) on potassium cyanide (KCN) -induced hypoxic cytotoxicity in rat pheochromocytoma cell line PC12, and to understand the ...

In cerebellar granule cells, potassium cyanide (KCN) activates the NMDA receptor resulting in generation of nitric oxide and reactive oxygen species (ROS). To study the mechanism by which KCN stimulates ROS generation, the action of cyanide on the enzymatic pathways known to generate ROS were studied. The oxidant-sensitive fluorescent dye, 2,7-dichlorofluorescin was used to measure intracellula...

In clinical or experimental studies of blood ascorbic acid, it is obviously important to maintain the ascorbic acid at its original level until analysis has been made. Pijoan, Townsend, and Wilson (1) reported a loss of about one-half of the vitamin C of blood plasma when the latter stood for 90 minutes at room temperature. Pijoan and Klemperer (2) recommended the addition of 1 mg. of KCN per c...

purpose: in the present study we have tried to find the most reliable intraocular lens (iol) power calculation formula in patients with keratoconus (kcn) and cataract. methods: in a prospective case series between october 2010 and march 2012, eligible patients with cataract and kcn underwent phacoemulsification with iol implantation. preoperatively, based on iol master keratometric data iol pow...

Machine learning models have recently provided great promise in diagnosis of several ophthalmic disorders, including keratoconus (KCN). Keratoconus, a noninflammatory ectatic corneal disorder characterized by progressive cornea thinning, is challenging to detect as signs may be subtle. Several machine been proposed KCN, however most the are supervised and thus require large well-annotated data....

PURPOSE To determine the prevalence of keratoconus (KCN) and subclinical KCN among subjects with two or more diopters (D) of astigmatism, and to compare Pentacam parameters among these subjects. METHODS One hundred and twenty eight eyes of 64 subjects with astigmatism ≥2D were included in the study. All subjects underwent a complete ophthalmic examination which included refraction, visual acu...

Systematic reviews of scientific literature are important for mapping the existing state of research and highlighting further growth channels in a field of study, but systematic reviews are inherently tedious, time consuming, and manual in nature. In recent years, keyword co-occurrence networks (KCNs) are exploited for knowledge mapping. In a KCN, each keyword is represented as a node and each ...

Isolated photophores of Porichthys notatus, maintained in saline at 20 degrees C, do not luminesce and show an oxygen consumption rate of 0.07 +/- 0.01 nmol min-1 photophore-1. In the presence of 10(-6) M-KCN, the photophores do not luminesce but the resting respiration decreases by about 50%. In the presence of 10(-5) M-KCN, some photophores do not luminesce and their respiration rate decrease...

Endogenous coupled respiration of Micrococcus luteus protoplasts showed a relatively high resistance to low concentrations of KCN, 2-nonyl-4-hydroxyquinoline N-oxide (NQNO) and dicyclohexylcarbodi-imide (DCCD) when the inhibitors were applied individually. In the presence of both KCN and NQNO (or DCCD), O2 uptake was strongly inhibited. The proteolysis of external membrane proteins of protoplas...