This chapter describes the basic protocols for solid-phase peptide synthesis using the Fmoc group as the N (α)-protecting group (Fmoc-SPPS). The chapter introduces resins and their handling, choice of linkers, and the most common methods for peptide chain assembly. The proper choice of resins and linkers for solid-phase synthesis is a key parameter for successful peptide synthesis. This chapter...

The purpose of this chapter is to explore organizational knowledge-based practices. A distinguishing feature of the successful post-Network Age enterprise is its intrinsic entrepreneurial character that manifests itself in key organizational knowledge practices relating to organizational culture, processes, content, and infrastructure. The chapter reports on the outcome of field research in whi...

Actin filaments and cross-linkers are main components of cytoskeletal networks in eukaryotic cells, and they support bending moments and axial forces respectively. A three-dimensional form-finding model is proposed in this work to investigate affine and non-affine deformations in cytoskeletal networks. In recent studies, modeling of cytoskeletal networks turns out to be a key piece in the cell ...

In the United States, tobacco control activities are organized primarily in state tobacco control programs. These programs are comprised of public and private agencies working together to reduce tobacco use. The human, financial, and informational resources that go into state tobacco control programs are documented, and the outcomes of these programs have been studied in terms of health and hea...

organizational cynicism is one of the issues that attract the interest of behavioral scholars and scientists because of its impact on the organizational performance. the goal of this research is measuring the level of organizational cynicism in employees of qom universities. in terms of goal, this is an applied research while it is a descriptive survey-type in terms of data collection method. t...

Citation Van der Veen, Annemarthe G. et al. " Role of the Ubiquitin-like Protein Urm1 as a Noncanonical Lysine-directed Protein Modifier. Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. The MIT Faculty has made this article openly available. Please share how this access benefits yo...