The amygdala has emerged as an important forebrain modulator of arousal. Acetylcholine plays a role in the regulation of sleep and wakefulness, particularly rapid eye movement sleep (REM). The major cholinergic input to the amygdala comes from the basal forebrain, a region primarily linked to wakefulness. We examined sleep and the encephalogram for 8 h following bilateral microinjections into t...

BACKGROUND Scalp cooling is a long known method to reduce chemotherapy-induced alopecia in cancer patients with solid tumors. Due to a progress in this method, a medical device enabling individual feedback-controlled temperature regulation was evaluated. Between June 2011 and December 2012, 83 breast cancer patients were included. Evaluation was focussed on the quantification of alopecia, satis...

Bioassay-guided fractionation of the ethyl acetate extract from Teucrium flavum subsp. glaucum, endowed with inhibitory activity towards HIV-1 reverse transcriptase–associated RNase H function, led to isolation salvigenin (1), cirsimaritin (2) and cirsiliol (3) along neo-clerodanes teuflavin (4) teuflavoside (5). Acid hydrolysis inactive provided three undescribed neo-clerodanes, flavuglaucins ...

Background: Odontogenic tumors are derived from the epithelial and/or mesenchymal remnants of the tooth-forming apparatus. Therefore, they are found exclusively in tooth-bearing areas. Similar to other neoplasms in the body, odontogenic tumors tend to histologically mimic the cell or tissue of origin. Case history: A 5-year-old boy presented with a chief complaint of pain in the mandible whi...

Begun in 2021, the first team encounter of project “Conques Global World” generated an innovative reinterpretation site. Departing from nineteenth- and twentieth-century explication Conques as ideal image Romanesque Middle Ages, site is here envisaged a space memorialization past for present. This memorialization, we argue, began fact at church’s conception, with founders’ decision to reflect c...