BACKGROUND Different factors contribute to the onset of labor at term. In animal models onset of labor is characterized by an inflammatory response. The role of intrauterine inflammation, although implicated in preterm birth, is not yet established in human term labor. We hypothesized that intrauterine inflammation at term is associated with spontaneous onset of labor. METHODS/RESULTS In two ...

OBJECTIVE To describe the pattern of labor progression and risk of cesarean delivery in women whose labor was electively induced. METHODS We analyzed data on all low-risk, nulliparous women with an elective induction or spontaneous onset of labor between 37 + 0 and 40 + 6 weeks from January 2002 to March 2004 at a single institution. The median duration of labor by each centimeter of cervical...

background post-term pregnancy is an important factor in perinatal mortality and morbidity. generally, to reduce perinatal mortality in pregnancy, the delivery is done before adverse perinatal morbidity occurs. to prevent prolonged pregnancy, labor is induced with chemical drugs and complementary therapies. due to the side effects and contraindications of chemical medicine, the use of herbs has...

There is no consensus on the optimal local anesthetic agent to initiate labor analgesia for patients in active labor. Currently used local anesthetic agents for initiating labor analgesia include 0.25% bupivacaine, 0.5% bupivacaine, 0.2% ropivacaine without or with various types and doses of opioids. All these agents are administered in incremental doses and are relatively "slow onset" in initi...

background: unripe cervix is one of the most causes of failure of labor induction. there are different methods for labor induction, which may differ depending on its duration. this study was performed to compare the effectiveness of vaginal misoprostol intravenous and oxytocin for induction of labor on hospitalized patients. methods: in a randomized clinical trail 110 pregnant women with bishop...

BACKGROUND There are no prospective studies that evaluated airway changes during labor. The purpose of this study was to evaluate airway changes in women undergoing labor and delivery. METHODS Two studies were undertaken to evaluate airway changes during labor. The first study used the conventional Samsoon modification of the Mallampati airway class. The airway was photographed at the onset a...

Identification of the onset of true labor has been one of the most difficult and critical challenge facing obstetric in maternity care. Predicting when true labor will start and recognizing when labor actually starts is important for both normal and complex pregnancies. For normal pregnancy, onset of true labor is important for reducing hospital costs as it will avoid admission when mother is n...

We have previously reported that intrauterine (i/u) administration of epidermal growth factor (EGF 500 ng) on day (d) 21 of pregnancy delayed 19.0 +/- 0.6 h the onset of labor. Progesterone (P) is secreted by ovarian corpora lutea (CL) throughout gestation in the rat. Prepartum CL regression due to increased uterine cyclooxygenase I and prostaglandin F(2alpha) results in P withdrawal followed b...