AIMS: Hydrogen sulfide (H2S) is a vasoactive gasotransmitter that is endogenously produced in the vasculature by the enzyme cystathionine gamma-lyase (CSE). However, the importance of CSE activity and local H2S generation for ischemic vascular remodeling remains completely unknown. In this study, we examine the hypothesis that CSE critically regulates ischemic vascular remodeling involving H2S ...

Using pharmacological and biochemical approaches, Ca2+ involved in the betulin production in mycelia of Phellinus linteus induced by hydrogen sulfide (H2S) were investigated. The results showed that 2 mM H2S donor NaHS or 10 mM CaCl2 was found to enhance the betulin content in the mycelia of Phellinus to the maximum, which were 112.43 and 93.24 % higher than that in the control, respectively. F...

Nitric oxide (NO) and hydrogen sulfide (H2S) pathways are involved in the development of hypertension, a condition that can originate from early life. We examined whether asymmetric dimethylarginine (ADMA, a nitric oxide synthase inhibitor)/NO and H2S generating pathway contributed to programmed hypertension in offspring exposed to prenatal dexamethasone (DEX) and postnatal high-fat (HF) and wh...

Recensione di Emanuela Piga Bruni, La macchina fragile. L’inconscio artificiale fra letteratura, cinema e televisione (Carocci, 2022).

This volume presents the critical edition of Cammino di Dante, first topo-chronographic summary Dante's Comedy, written by Florentine notary, ser Piero Bonaccorsi (1410-1477), for friar Santa Croce, Romolo de' Medici. The text is opened a bio-bibliographical introduction on author, that hightlights some new aspects his notarial career, literary activity and relationship with notable figures age...

Riassunto: Questo contributo riflette le conoscenze acquisite in letteratura nello studio della mortalità dei bambini in Italia nel XIX secolo e nei primi decenni del secolo successivo, con speciale riferimento al tema delle determinanti della sopravvivenza infantile. La prima parte è una rassegna delle principali ipotesi avanzate a quest’ultimo riguardo dagli studi “ecologici”. Partendo da que...

English. Several unsupervised methods for hypernym detection have been investigated in distributional semantics. Here we present a new approach based on a smoothed version of the distributional inclusion hypothesis. The new method is able to improve hypernym detection after testing on the BLESS dataset. Italiano. Sulla base dei metodi non supervisionati presenti in letteratura, affrontiamo il t...