The title compound, {[BaPt(CN)(4)(C(12)H(26)N(2)O(4))]·0.5H(2)O}(n), is a two-dimensional coordination polymer in which the sheets are oriented approximately parallel to the (01) set of crystal planes. In the crystal structure, disordered water mol-ecules (half occupancy) connect the sheets into a three-dimensional network via inter-molecular O-H⋯O hydrogen bonds. An N-H⋯N inter-action is also ...

levofloxacin is one of the fluroquinoline antibiotic groups, which affect on controlling infections, especially in reproductive organs. it has therapeutic use in numerous countries, but little information exists on the effects of levofloxacin on spermatogenesis when it is used for infectious treatment. the current study was designed to determine whether levofloxacin influences testis tissue and...

In the crystal structure of the title compound {systematic name: (1'S,2R,2'R,3'S,6'R)-3'-ethyl-4-methyl-5H-5'-oxa-10'-aza-spiro-[furan-2,4'-tricyclo-[8.3.0.0(2,6)]trideca-ne]-5,11'-dione hemihydrate}, C(17)H(23)NO(4)·0.5H(2)O, the asymmetric unit contains two mol-ecules of tuberostemoamide with similar conformations and one water mol-ecule. The tuberostemoamide mol-ecule is composed of one seve...

The development of a new class of antibiotics to fight bacterial resistance is a time-consuming effort associated with high-cost and commercial risks. Thus, modification, conjugation or combination of existing antibiotics to enhance their efficacy is a suitable strategy. We have previously reported that the amphiphilic cyclic peptide [R₄W₄] had antibacterial activity with a minimum inhibitory c...

The aim of this study was to determine the transport and distribution characteristics of levofloxacin in the rat stomach and investigate the effects of combination treatment with rabeprazole. A total of 160 Wistar rats were randomly divided into four treatment groups: 50 mg/kg levofloxacin, 100 mg/kg levofloxacin, 50 mg/kg levofloxacin + rabeprazole and 100 mg/kg levofloxacin + rabeprazole. For...

the present study was conducted on five healthy male cross bred calves to study the kinetic dispositionand urinary excretion of levofloxacin following its single subcutaneous administration at the dose of4 mg.kg-1. the concentration of levofloxacin in plasma and urine samples was estimated by microbiologicalassay. peak plasma level of levofloxacin (2.8 ± 0.3 μg.ml-1) was observed at 45 min and ...