BACKGROUND AND AIMS Major liver resection incurs a risk of postoperative liver dysfunction and infection and there is a lack of objective evidence relating residual liver volume to these complications. PATIENTS AND METHODS Liver volumetry was performed on computer models derived from computed tomography (CT) angioportograms of 104 patients with normal synthetic liver function scheduled for li...

AIM To determine the incidence and factors associated with drug induced hepatic dysfunction in children on anti-tuberculous treatment (ATT). SETTING Pediatric Tuberculosis Clinic at B.J. Wadia Children's Hospital, Mumbai. MATERIAL AND METHODS 46 children with tuberculosis on ATT between April 2007 and February 2008 were included. Serum glutamic pyruvic transaminase (SGPT) level was measured...

Regular packed cell transfusion in patients with thalassemia major leads to iron overload. Chelation therapy is one of the important aspects of thalassemia care as iron overload causes significant cardiac, hepatic, and endocrine dysfunction. We report a case of thalassemia major with severe iron overload causing cardiac and liver dysfunction who benefitted from triple drug chelation therapy. Tr...

Liver dysfunction is one of the most recognized complications in patients with acute heart failure (HF) and therefore a liver function score may be useful for risk-stratification those patients. Recently, albumin-bilirubin (ALBI) was developed as new model to assess disease. We explored association between ALBI at admission in-hospital mortality HF.

Liver dysfunction plays a significant role in the Intensive Care Unit (ICU) patients’ morbidity and mortality. Metabolic, hemodynamic and inflammatory factors contribute in liver damage. Hemorrhagic shock, septic shock, multiple organ dysfunction, acute respiratory dysfunction, metabolic disorders, myocardial dysfunction, infection from hepatitis virus, and therapeutic measures such as blood tr...

The purpose of the present study was to investigate the threshold dose for focal liver damage after stereotactic body radiation therapy (SBRT) in cirrhotic and normal livers using magnetic resonance imaging (MRI). A total of 64 patients who underwent SBRT for liver tumors, including 54 cirrhotic patients with hepatocellular carcinoma (HCC) and 10 non-cirrhotic patients with liver metastases, we...

objectives the main aim of this study was to evaluate the usefulness of applying extracorporeal liver support techniques to treat this group of patients. patients and methods the data from 23 hospital admissions of 21 patients with ald who were admitted to the department of anesthesiology and intensive therapy (a⁢) at the dr wł. biegański regional specialist hospital in łódź between march 20...

introduction drug-induced liver injury is a frequent cause of hepatic dysfunction. several drugs have been identified to cause autoimmune hepatitis (aih). environmental chemicals are capable of triggering a certain degree of liver injury. however, toxin induced aih is rare. conclusions chronic (long-term) exposures to dichlorvos can lead to aih. a detailed inquiry of medical history and liver b...