BackgroundCongenital generalized lipodystrophy (CGL) is a rare disease. It is associated with near total fat loss, severe insulin resistance and hypoleptinemia leading to metabolic derangements.Case PresentationWe report a 25- year- old female with 1-Acylglycerol-3-phosphate-O-acyltransferase 2 (APGAT2) mutation, and both sclerotic and lytic bone lesions together for the first time. Bone cyst i...

simple bone cysts are usual, benign, fluid-filled, cystic lesions that often occur in the metaphysis of the long bones and are rarely detected in vertebrae. a case of a simple bone cyst in the body of the fifth lumbar vertebra in a 28-year-old woman with complaint of intermittent low back pain is described. according to the radiologic findings, the lesion was detected as a simple bone cyst, and...

Objective- To evaluate the role of greater omentum incorporation of coral in healing of the long bone defect in dog model. Design- Experimental in-vivo study. Animals- Sixteen adult mongrel male dogs weighing 26.2±2.5 kg, free of evident infectious or parasitic illnesses were used in this study. Procedures- The operative procedure was undertaken under general anesthesia. Radial bone was expo...

background: corticosteroids (cs) are used widely for their anti-inflammatory and immunosuppressive properties. they have the potential to cause dramatic improvement as well as produce equally dramatic adverse effects. the clinical misuse like over prescription of the drug should be avoided. long-term administration may cause many adverse effects leading to impaired oral health. oral health is u...

abstract non-:union: occurs when bone healing ceases and does not continue without some type of intervention. classification of non-:union: is traditionally based on the amount of callus or bone healing at the fracture site. successful treatment of non-:union: often depends on appropriate reduction and realignment of the fracture, bone grafting if necessary, and stabilization. this may not be p...

Primary angiosarcoma of bone is very rare.It occurs more commonly in middle-age and later life, with a male predominance in the ratio of 2:1. Angiosarcoma of bone has a tendency to involve the long tubular bones, and multifocal involvement is common. Here, we present a case of a 69-yr-old man in Shahid Sadooghi Hospital of Yazd in 2014 that had angiosarcoma of the left tibia. He was treated wit...