نتایج جستجو برای: long noncoding rna
تعداد نتایج: 1007963 فیلتر نتایج به سال:
Transcription occurs across more than 70% of the human genome and half currently annotated genes produce functional noncoding RNAs. Of these transcripts, majority—long, RNAs (lncRNAs)—are greater 200 nucleotides in length are necessary for various roles cell. It is increasingly appreciated that lncRNAs relevant both health disease states, with brain expressing largest number compared to other o...
Animal cells possess thousands of long non-coding (lnc) RNAs, such as antisense noncoding RNA in the INK4 locus (ANRIL) , which have regulatory roles in the cells’ molecular mechanisms, including X-chromosome inactivation, and developmental processes. These lnc RNAs are known to influence the extensive spectrum of age-related disorders. Accordingly, there is evidence for the role of...
Prostate cancer is considered the second most common visceral malignancy in men in Western countries. Its emergence is largely due to the coordination of a malignant network, and long noncoding RNA has been recently demonstrated to play a critical role in prostate carcinogenesis. The aberrant expression of long noncoding RNA in prostate cancer patients is strongly associated with diagnosis, ris...
T cells tell macrophages when to start making the toxic soup of lysosomal enzymes, reactive oxygen species, and nitric oxide that destroys intracellular pathogens. In 1983, Carl Nathan proved that this start signal comes in the form of the secreted cytokine IFNgamma.
Long-chain noncoding RNA (lncRNA) is a new class of molecular regulators in heart development and disease. However, the role specific lncRNA cardiac fibrosis remains to be fully explored. This study aimed investigate potential mechanism MHRT myocardial after infarction (MI).
Introduction Approximately three-quarters of the mammalian genome is transcribed into RNA (1–3); however, only a fraction of this transcription produces mRNA, whose mature nucleotide sequence serves as a template for protein synthesis (3). The function of this nonprotein-coding RNA (or noncoding RNA) is mostly obscure, despite a larger number of noncoding genes than protein-coding genes. Given ...
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