نتایج جستجو برای: methacholine challenge test
تعداد نتایج: 1009780 فیلتر نتایج به سال:
Methacholine, provided by industrial sources, has traditionally been used in studies of airways responsiveness. In 1986, a Food and Drug Administration approved formulation of methacholine (Provocholine) was released and replaced industrial methacholine in many pulmonary laboratories. To determine whether methacholine and Provocholine cause an equivalent degree of bronchoconstriction, a double ...
OBJECTIVE To evaluate bronchial challenges using three different stimuli as screening tools for bronchial hyper-responsiveness in sulfur mustard gas-induced asthma. DESIGN Randomized, cross-over clinical study. SETTING University hospital. PATIENTS Eighteen veterans with mustard gas-induced asthma and 18 normal veterans as the control group. INTERVENTION Pulmonary function tests and inh...
RATIONALE Bronchial hyperresponsiveness (BHR) is an important, but not specific, asthma characteristic. OBJECTIVES We aimed to assess the predictive value of BHR tested by methacholine and exercise challenge at age 10 years for active asthma 6 years later. METHODS From a Norwegian birth cohort, 530 children underwent methacholine challenge and exercise-induced bronchoconstriction (EIB) test...
3-hydroxy-3-methylglutaryl-coa reductase inhibitors (statins), are effective serum cholesterol-lowering agents which also have anti-inflammatory properties. the objective of this study was to evaluate the effect of atorvastatin on bronchial hyperresponsiveness. adult patients (age 14 to 65 years) with bronchial hyperresponsiveness (bhr) diagnosis based on the spirometry with methacholine challe...
A 20-year-old white female nonsmoker presented to the pulmonary function laboratory for a methacholine challenge test. The patient denied wheezing, dyspnea, cough, or chest tightness. In fact, she competes in collegiate basketball and softball without respiratory complaints. She stated that her primary care physician wanted to “screen her for asthma,” because her father is asthmatic. Her medica...
This international task force report updates general considerations for bronchial challenge testing and the performance of the methacholine challenge test. There are notable changes from prior recommendations in order to accommodate newer delivery devices. Rather than basing the test result upon a methacholine concentration (provocative concentration (PC20) causing a 20% fall in forced expirato...
Asthma is a complex disease of airway inflammation, which results in airway remodeling and hyper-responsiveness.1 Because asthma-related symptoms are not specific to asthma, diagnosis requires objective data from pulmonary function tests (PFT). Bronchodilator responsiveness and airway responsiveness to provocational stimuli (eg, methacholine, dry-gas hyperpnea) help establish the diagnosis of a...
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