background and objective: regarding inefficiency of common drugs used for alleviation of anxiety due to narcotics withdrawal, the present study was evaluated methadone and haloperidol co-drugs therapy on anxiety due to morphine withdrawal. materials and methods: ninety eight nmri male mice were divided into acute and chronic experimental groups. then, each group was divided into 7 subgroups: sa...

AIM To analyze the success of three different treatment modalities for heroin addiction: methadone therapy, hospital therapy without methadone, and therapeutic community. METHODS Ninety heroin addicts from the city of Split, Croatia, were systematically allocated to three groups, with 30 participants each, according to the addiction treatment modality they underwent or treatment that resulted...

background due to the chronic and recurrent nature of addiction, many people who quit drug addiction may slip back into the pattern of using drugs shortly after the detoxification period. emotion-regulation strategies and resilience play an important role in preventing the recurrences of substance abuse. objectives this study aimed to compare the effects of methadone-maintenance therapy (mmt) a...

addiction to the illicit and prescribed use of opiate is an alarming public health issue. studies on addictive disorders have demonstrated severe nutritional deficiencies in opiate abusers with behavioral, physiological and cognitive symptoms. opiate addiction is also link with a significant number of diseases including human immunodeficiency virus (hiv), hepatitis c virus (hcv) and other blood...

Background: Evaluation of sexual disorders among persons receiving methadone replacement therapy is of great importance, because these problems may lead to non-compliance and relapse. This study aimed to estimate the effect of methadone maintenance therapy (MMT) on sexual function among addicted Iranian men using met-analysis.Methods: Investigating the available data banks, relevant studies wer...

background opium abuse significantly affects the nutritional status of users and frequently leads to undernourishment. methadone maintenance therapy has been used as one of the possible ways to prevent of infection diseases such as hiv and hepatitis b and c and improve the quality of life in opioid-dependent patients. objectives the aim of this study was to assess the anthropometric and socio-d...

BACKGROUND Concern regarding the QTc interval in human immunodeficiency virus (HIV)-infected patients has been growing in recent years, and cases of prolonged QTc interval and torsades de pointes have been described in HIV-infected patients on methadone therapy. This study aimed to determine the prevalence and factors associated with long QTc interval in a cohort of opioid-dependent HIV-infecte...

Background Methadone, a full opioid agonist, and buprenorphine, partial agonist at the receptor, are established first-line medications for maintenance therapy. Transition from methadone to sublingual buprenorphine may precipitate withdrawal is usually performed only in patients on low dose of (<30–40 mg). novel subcutaneous depot (Buvidal) has not been previously described.Objectives To test h...