نتایج جستجو برای: microarray
تعداد نتایج: 47705 فیلتر نتایج به سال:
background: the microarray technology is in needed of cost-effective, low background noise and stable substrates for successful hybridization and analysis. methods: in this research, we developed a three-dimentional stable and mechanically reliable microarray substrates by coating of two polymeric layers on standard microscope glass slides. for fabrication of these substrates, a thin film of ox...
Background and Objective: In recent years, DNA microarray technology has become a central tool in genomic research. Using this technology, which made it possible to simultaneously analyze expression levels for thousands of genes under different conditions, massive amounts of information will be obtained. While traditional clustering methods, such as hierarchical and K-means clustering have been...
Introduction & Objective: The link between dietary fat and coronary heart disease has attracted much attention since the effect of long?chain fatty acids (LCFA) on gene transcription has been established, which in part, these effects can be explained by the regulation of gene transcription. In this study, the P19CL6 cardiac cell?line was targeted for the investigation of (i) the effects of long...
Extracellular exosomes and preeclampsia: a microarray-based study and functional enrichment analysis
Background: Preeclampsia (PE) is a heterogeneous pregnancy disease which the exact pathophysiology of it is unknown. Recently exosomes have been indicated as a causative factor in the pathogenesis of PE. The aim of the study was to investigate in microarray library data to extract the differentially expressed genes (DEGs) in PE and to perform a functional enrichment analysis to predict the rol...
component-resolved diagnosis (crd) using microarray technology has recently been introduced with the aim to improve diagnosis of allergy. the aim of this study was to compare performance of this allergen microarray to those of an established extract-based skin prick testing (spt). 45 patients with allergic rhinitis were studied (16 children and 29 adults). spt to dermatophagoides ...
The DNA microarray is an important technique that allows researchers to analyze many gene expression data in parallel. Although the data can be more significant if they come out of separate experiments, one of the most challenging phases in the microarray context is the integration of separate expression level datasets that have gathered through different techniques. In this paper, we prese...
Chemoresistance is one of the main obstacles to the success of cancer treatment and one of the most important causes of death in patients. In the last decade, progress in high-throughput technologies, including microarray, sequencing, and bioinformatics has greatly resulted in cancer gene profiling and identification of biomarkers for cancer prognosis and prediction. This has greatly improved t...
microarray data have an important role in identification and classification of the cancer tissues. having a few samples of microarrays in cancer researches is always one of the most concerns which lead to some problems in designing the classifiers. for this matter, preprocessing gene selection techniques should be utilized before classification to remove the noninformative genes from the microa...
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