This paper presents a multi-objective mathematical model which aims to optimize and harmonize supply chain reduce costs, improve quality, achieve competitive advantage position using meta-heuristic algorithms. The purpose of optimization in this field is increase quality customer satisfaction production time related prices. present research simultaneously optimized the multi-product multi-perio...

This research concerns a type of configuration optimization problems frequently encountered in engineering design and manufacturing, where the envelope volume in space occupied by a number of components needs to be minimized along with other objectives such as minimizing connective lines between the components under various constraints. Since in practical applications the objectives and constra...

Masonry bricks were widely used in construction of the walls most Chinese historical buildings. The low strength lime–clay mortar existing brick masonry has usually led to poor performance such as cracking and collapse during earthquakes. As composition modified oyster shell ash (MOSA mortar) with higher is similar that mortar, it can be partially replace original for buildings order improve th...

Introduction A dedicated emicizumab assay based on the modified one-stage factor VIII (FVIII) (mOSA) is mainly available in haemophilia treatment centres (HTC). method to estimate plasma levels a widely would be desirable, especially for emergency situations. Aim level approximation (ELA) using routine FVIII activity measurement with standard (sOSA) was developed and evaluated. Method Within th...

Time-dependent Vehicle Routing Problem is one of the most applicable but least-studied variants of routing and scheduling problems. In this paper, a novel mathematical formulation of time-dependent vehicle routing problems with heterogeneous fleet, hard time widows and multiple depots, is proposed. To deal with the traffic congestions, we also considered that the vehicles are not forced to come...

SXT is an integrative and conjugative element (ICE) that confers resistance to multiple antibiotics upon many clinical isolates of Vibrio cholerae. In most cells, this approximately 100 Kb element is integrated into the host genome in a site-specific fashion; however, SXT can excise to form an extrachromosomal circle that is thought to be the substrate for conjugative transfer. Daughter cells l...

Reverse logistics, which is induced by various forms of used products and materials, has received growing attention throughout this decade. In a highly competitive environment, the service level is an important criterion for reverse logistics network design. However, most previous studies about product returns only focused on the total cost of the reverse logistics and neglected the service lev...

This study proposes a cross-domain multi-objective speech assessment model, called MOSA-Net, which can simultaneously estimate the quality, intelligibility, and distortion scores of an input signal. MOSA-Net comprises convolutional neural network bidirectional long short-term memory architecture for representation extraction, multiplicative attention layer fully connected each metric prediction...