نتایج جستجو برای: mucociliary clearance
تعداد نتایج: 48254 فیلتر نتایج به سال:
BACKGROUND Cilia are complex and powerful cellular structures of the respiratory mucosa that play a critical role in airway defense. Respiratory epithelium is lined with cilia that perform an integrated and coordinated mechanism called mucociliary clearance. Mucociliary clearance is the process by which cilia transport the mucus blanket overlying respiratory mucosa to the gastrointestinal trac...
Chronic bronchitis is in part characterized by mucus hypersecretion and the inability to clear airways of mucus. Despite years of research in this area, to date there are no pharmacologic therapies available to enhance or promote mucociliary clearance. P2Y(2) receptor agonists are a new class of mucoactive compounds that are currently under development for this purpose. This article will review...
Mucociliary clearance depends on the interaction between cilia and mucus; it is delayed in the presence of purulent secretions. Nasal mucociliary clearance was examined by the saccharin method and nasal ciliary beat frequency by a photometric technique. Four groups were studied: normal controls, patients with bronchiectasis without nasal symptoms, patients with chronic mucopurulent sinusitis al...
MUCOCILIARY CLEARANCE plays a crucial host-defense role in both the upper and lower airways, providing protection from a wide variety of airborne hazards including allergens, pathogens, and environmental toxins. Proper function of the mucociliary clearance system depends on the structure and function of the cilia as well as the composition of the airway surface liquid layer. The mucus component...
OBJECTIVES There is evidence that outdoor workers exposed to high levels of air pollution exhibit airway inflammation and increased airway symptoms. We hypothesized that these workers would experience increased airway symptoms and decreased nasal mucociliary clearance associated with their exposure to air pollution. METHODS In total, 25 non-smoking commercial motorcyclists, aged 18-44 years, ...
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