Medically, the oil-in-water nanosized emulsions are used mainly as delivery carriers for lipophilic drug molecules which show therapeutic activity when administered via parenteral, ocular and transdermal routes. To extract multifunctional activities, the nanosized emulsions containing neutral, anionic and cationic charges over dispersed oil droplets are designed with the help of variety of exci...

Despite the world wide adaptability of herbal plants and their products, these conventional drugs suffering with many pharmacological and pharmacokinetics constraints. Major drawbacks related with these traditional drugs includes low aqueous solubility and physical stability, reduce absorption, rapid metabolism, instability under high acidic conditions and inability to cross blood-brain barrier...

The objective of this study was to produce well-dispersed nanosized yttria tetragonally stabilized zirconia (Y-TZP) powder in aqueous suspension. The Y-TZP powder was produced by precipitation from homogeneous solution at 2001C under hydrothermal conditions. A homogeneous solution was created through the use of a complexing agent, which subsequently could be used in a dispersion scheme develope...

Delivery of drug through topical route represents a most convenient and novel approach. The major difficulty arises while delivering a drug through skin is its action as a natural barrier nature which makes it difficult for most drugs to penetrate into and permeate through it. Conventional topical formulations have not proved to be effective in dermal delivery of drug. Novel drug delivery syste...

The synthesis of the ZSM-5 and beta zeolites in their nanosized form has been achieved by using simple alkyl-substituted mono-cationic cyclic ammonium cations as OSDA molecules. The particular combination of a cyclic fragment and a short linear alkyl-chain group (preferentially C4) within the monocationic OSDA molecules allows directing the crystallization of nanosized zeolites with excellent s...

Celecoxib, a selective cyclo-oxygenase – 2 inhibitor has been recommended orally for the treatment of arthritis and osteoarthritis. Long term oral administration of celecoxib produces serious gastrointestinal side effects. Therefore the aim of the present investigation was to assess the potential of nanosized emulsion formulations for transdermal delivery of celecoxib (CXB), to reduce the side ...

Many cell types release nanosized vesicles derived from endosomal compartments (exosomes) or the plasma membrane. Vesicles actively released by CD4(+) T cells have immune-modulatory characteristics. Using our recently developed high-resolution flow cytometry-based method for the analysis of individual nanosized vesicles, we here investigated how T cell receptor (TCR)-triggering and co-stimulato...

When reductive gases pass over the surface of nanosized catalysts, a kind of chemiluminescence named cataluminescence (CTL) can be generated due to the production of excited intermediates. Here we report the observation of an energy transfer process between excited intermediates and the nanosized catalysts. The CTL is quenched when introducing Ho3+, Co2+ and Cu2+ into the catalyst, while new in...

Nanosized MOR and BEA zeolites were directly synthesized using simple diquaternary ammonium compounds. The nanosized show improved catalytic performance in Friedel–Crafts n -alkane hydroconversion reactions.