نتایج جستجو برای: nefl
تعداد نتایج: 100 فیلتر نتایج به سال:
Myxopapillary ependymoma (MEPN) generally can be cured by gross total surgical resection and usually manifest a favorable prognosis. However, surgery is less curative in tumors that are large, multifocal or extend outside the thecal sac. Late recurrences may occur, particularly in pediatric patients. The role of adjuvant therapy is unclear in the clinical management of recurrent tumors. Clinica...
Charcot-Marie-Tooth (CMT) disease or hereditary motor and sensory neuropathy is the most prevalent inherited peripheral neuropathy and is associated with over 90 causative genes. Mutations in neurofilament light polypeptide gene, NEFL cause CMT2E, an axonal form of CMT that results in abnormal structures and/or functions of peripheral axons in spinal cord motor neurons and dorsal root ganglion ...
Ependymomas occur in both the brain and spine. The prognosis of these tumors sometimes differs for different locations. The genetic landscape of ependymoma is very heterogeneous despite the similarity of histopathologic findings. In this review, we describe the genetic differences between spinal ependymomas and their intracranial counterparts to better understand their prognosis. From the liter...
Neuroblastoma is a lethal tumor that mainly occurs in children. To date, the genetic etiology of sporadic neuroblastoma remains obscure. A previous study identified three neuroblastoma susceptibility loci (rs11994014 G>A, rs2979704 T>C, rs1059111 A>T) in neurofilament light (NEFL) gene. Here, we attempted to evaluate the contributions of these three single nucleotide polymorphisms to neuroblast...
سلول¬های بنیادی بافت چربی توانایی تمایز به رده¬های مزودرمی، اندودرمی و اکتودرمی را دارند. چندین مطالعه داده تمایز سلول¬های بنیادی بافت چربی به فنوتیپ¬های نورونی و گلیالی را نشان داده¬اند. هدف از مطالعه¬ی حاضر، تمایز سلول¬های بنیادی بافت چربی انسان به نورون¬های دوپامینرژیک در محیط کشت است. مواد و روش¬ها: به این منظور، سلول¬های بنیادی از بافت چربی حاصل از جراحی آبدمینوپلاستی جداسازی شدند. جهت شنا...
We observed two surface spin-wave modes in ferromagnetic resonance in monocrystalline, epitaxial layers of manganese femte (NEFL). The layers, 2 3pn thick, were obtained by CVD on monocrystalline MgO substrates. In MEFL, observations were performed at room temperature and a frequency of 26.6 GHz. The critical angles for which the surface modes vanish amount to 48' and 37', respectively, for lin...
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