Immunosuppressant agents such as calcineurin inhibitors (CNI) used after solid organ transplantation may cause endothelial dysfunction, and coronary and renal arterial vasospasm. We report a patient presenting acute ST segment elevation myocardial infarction (STEMI) at the second week of renal transplantation. In the case of STEMI in patients with solid organ transplants under immunosuppressive...

A 13-year-old girl with right adrenal pheochromocytoma pretreated with Nifedipine, underwent surgical removal of the tumor. General anesthesia with Propofol infusion and pethidine analgesia was performed. To control the blood pressure (BP), Nitroglycerine infusions were administered successfully. Following the ligation of the adrenal veins, patient was hypotensive and inotropic support was requ...

Those who have started to read this review expecting a discussion of the political situation in Northern Ireland will either be relieved or disappointed. The title refers to the discovery and actions of nitric oxide and the role played by investigators in Northern Ireland, its relationship to the explosive nitroglycerine and the concepts of nitrate resistance and tolerance in cardiovascular med...

OBJECTIVES Hypertension is one of the most frequent complication during laryngoscopy and intubation; thus in the premedication or induction stages, many drugs have been used to control this hypertension. Nitroglycerine is one of the drugs thought to be effective and the purpose of this study is to appraise this deliberation. METHODS 150 patients of 20-50 years of age were enrolled in this ran...

Despite advances in the treatment of postoperative pain, many patients still suffer from pain after surgery, probably due to difficulties in balancing an effective postoperative pain treatment regimen with acceptable side effects. Intrathecal analgesia with a variety of drugs is a widely accepted practice for the treatment of both acute and chronic pain. The purpose of this study was to determi...

The efficacy of nitroglycerine, verapamil and nifedipine in controlling post-sternotomy hypertension was compared in four groups of 20 patients anaesthetized with fentanyl 100 micrograms kg-1 undergoing elective coronary artery surgery. Vasodilators were started before surgery and adjusted to maintain systolic arterial pressure less than 120% of pre-infusion values, the mean (+/- SEM) requireme...