This paper deals with a new Bayesian approach to the one-sample test for proportion. More specifically, let x=(x1,…,xn) be an independent random sample of size n from Bernoulli distribution unknown parameter θ. For fixed value θ0, goal is null hypothesis H0:θ=θ0 against all possible alternatives. The proposed based on using well-known formula Kullback–Leibler divergence between two binomial dis...

Proteomics is the large-scale study of an organism's complete complement of proteins, and its relevant technologies have matured over recent years. Along with the development of mass spectrometry (MS), MS-based proteomics has emerged as an invaluable tool for largescale identification and quantification of protein networks (Aebersold & Mann, 2003; Domon & Aebersold, 2006). Proteomic data is imp...

BACKGROUND Physical activity (PA) surveillance is an important component of non-communicable disease risk factor monitoring, and occurs through national and international surveillance systems. This review identifies population PA estimates for adults in the Asia-Pacific region, and examines variation in trends and prevalence rates obtained using different PA measures. METHODS Data were obtain...

CONTEXT Controversy and uncertainty ensue when the results of clinical research on the effectiveness of interventions are subsequently contradicted. Controversies are most prominent when high-impact research is involved. OBJECTIVES To understand how frequently highly cited studies are contradicted or find effects that are stronger than in other similar studies and to discern whether specific ...

Detection of interacting risk factors for complex traits is challenging. The choice of an appropriate method, sample size, and allocation of cases and controls are serious concerns. To provide empirical guidelines for planning such studies and data analyses, we investigated the performance of the multifactor dimensionality reduction (MDR) and generalized MDR (GMDR) methods under various experim...