OBJECTIVE To investigate the effects of a novel specific renin inhibitor, RO 42-5892, with high affinity for human renin (Ki = 0.5 x 10(-9) mol/l), on plasma renin activity and angiotensin II concentration and on 24 hour ambulatory blood pressure in essential hypertension. DESIGN Exploratory study in which active treatment was preceded by placebo. SETTING Inpatient unit of teaching hospital...

the main purpose of this study is the survey of the atmospheric low pressure effects at sea level oscillations in the qeshm channel. for this purpose, the curves of the pressure on the persian gulf and oman sea, during the passing of the atmospheric low pressure system, are extracted across the region. during the time of occurrence of these events, sea level oscillations in the coastal areas of...

We evaluated the effect of oral calcium supplementation on blood pressure, calcium metabolism, and insulin resistance in essential hypertension. After receiving a standard diet with 500 mg of calcium per day during a 4-week period, 20 nondiabetic, essential hypertensive patients were randomized in a double-blind fashion to receive oral calcium supplementation (1500 mg of calcium per day) or pla...

OBJECTIVE There are several treatments for obstructive sleep apnea syndrome, such as weight loss, use of an oral appliance and continuous positive airway pressure, that can be used to reduce the signs and symptoms of obstructive sleep apnea syndrome. Few studies have evaluated the effectiveness of a physical training program compared with other treatments. The aim of this study was to assess th...

introduction: oral mucositis is considered a severe complication in cancer patients receiving radiotherapy or chemotherapy for head and neck cancer. the aim of this review study was to assess the effect of low level laser therapy for prevention and management of oral mucositis in cancer patients. methods: the electronic databases searched included pubmed, isi web of knowledge and google scholar...

background: although a variety of methods have been suggested to reduce stress, anxiety and pain intensity due to spinal needle skin puncture, their adverse effects restrict theirs widespread administration. in this study we evaluated the effects of oral tizanidine on the reduction of pain caused by spinal needle puncture and hemodynamic responses. methods : in this double blind randomized clin...