conclusions by controlling the modifiable risk factors and modality of treatment in our study, physicians can reach more effective treatment. results at the end of the study, long-term graft failure was seen in 27 (10.2%) cases. one-year and 2-year graft survival after diagnosis of cancer were 93.6% and 91.7%, respectively. the univariate analysis showed that the incidence of chronic graft loss...

hypertension is a common complication of kidney transplantation with the prevalence of 80%. studies in adults have shown a high prevalence of hypertension (htn) in the first three months of transplantation while this rate is reduced to 50- 60% at the end of the first year. htn remains as a major risk factor for cardiovascular diseases, lower graft survival rates and poor function of transplante...

Editorial Protocol biopsies should not (yet) be the standard of care in pediatric renal transplant recipients The care and management of renal transplant recipients, and especially of pediatric renal transplant recipients, is potentially complex and exacting. Balancing the amount of immunosup-pression to prevent toxicity and to avoid rejection is not always straightforward. In addition, the spe...

Significant progress has been made in pediatric kidney transplantation. Advances in immunosuppression have dramatically decreased rates of acute rejection leading to improved short term graft survival but similar improvements in long term graft survival remain elusive. Changes in allocation policy provide the pediatric population with timely access to transplant but there remains concern about ...

BACKGROUND AND OBJECTIVES Immunosuppressive medications are essential in preventing kidney transplant rejection. Continuous insurance coverage for outpatient immunosuppressive medications remains a major issue. The objective of this study was to establish the prevalence and consequences of cost-related immunosuppressive medication nonadherence. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS A ...

cyclosporine (csa) is a drug that has been used for prevention of kidney transplant rejection for many years. diltiazem with the inhibition of cyclosporine metabolism and clearance will increase csa concentration and csa dose can be decreased. the aim of this study was the evaluation of diltiazem effect on csa dose adjustment with respect to c2. forty stable renal transplant patients who were r...

We analyzed the frequency of vesicoureteral reflux and the factors that favor its appearance after kidney transplantation in pediatric patients. This retrospective analysis examined the prevalence of post-transplant vesicoureteral reflux in a total of 181 kidney transplants performed in children at our center between 1978 and 2004. In patients who required corrective surgery for this problem, w...

BACKGROUND Relatively little is known about the management and outcomes of Aboriginal children with renal failure in Canada. We evaluated differences in dialysis modality, time spent on dialysis, rates of kidney transplantation, and patient and allograft survival between Aboriginal children and non-Aboriginal children. METHODS For this population-based cohort study, we used data from a nation...

OBJECTIVE To investigate changes in pediatric kidney transplant outcomes over time and potential variations in these changes between the early and late posttransplant periods and across subgroups based on recipient, donor, and transplant characteristics. METHODS Using multiple logistic regression and multivariable Cox models, graft and patient outcomes were analyzed in 17,446 pediatric kidney...