Periapical lesions are characterized by the destruction of periapical bone, and occur as a result of local inflammatory responses to root canal infection by microorganisms including Porphyromonas endodontalis (P. endodontalis). P. endodontalis and its primary virulence factor, lipopolysaccharide (LPS), are associated with the development of periapical lesions and alveolar bone loss. Interleukin...

The aim of this case report is to present two cases where cone beam computed tomography (CBCT) was used for the diagnosis, treatment planning, and followup of large periapical lesions in relation to maxillary anterior teeth treated by endodontic surgery. Periapical disease may be detected sooner using CBCT, and their true size, extent, nature, and position can be assessed. It allows clinician t...

BACKGROUND Osseous dysplasia (OD) is the most common fibro-osseous lesion of the jaw affecting the periapical region. Early stages of OD can resemble periapical radiolucencies, thus mimicking the radiological aspects of an endodontic pathology. Such radiolucent lesions affecting previously decayed or treated teeth are even more complex to interpret. CASE PRESENTATION The aim of this paper is ...

PURPOSE The aim of this study was to systematically review the evidence for periapical implant lesion, which makes a patient more susceptible to the periapical lesion, frequency, symptoms, signs (including radiological findings) and possible treatment options. MATERIAL AND METHODS A systematic literature review and analysis of publications included in PubMed, Embase and Cochrane; articles pub...

Odontogenic infections can result from several conditions, such as pulp necrosis, periodontal disease, pericoronitis, trauma, or surgery.  The three types of odontogenic dental abscesses are endodontal periapical, periodontal, and pericoronal, depending on where the infection first developed. Periodontal abscesses, which particularly common in people with untreated disease patients during ...

conclusions based on 8.2 mm cut-off point could differentiate 83% periapical granulomas and 79% radicular cysts from radiography images. background the distinction between radicular cysts and apical granulomas is important in treatment decision. objectives the current study aimed to differentiate these two lesions based on radiography images. results average size of radiography in periapical gr...

OBJECTIVE To evaluate the periapical repair after root canal treatment in the teeth of dogs using CT and conventional radiography and to compare these findings with the gold standard microscopic evaluation. STUDY DESIGN The animals were divided into three groups according to endodontic treatment performed: Group 1, single-visit endodontic treatment in teeth without apical periodontitis; Group...

background and aims. chronic periapical disease with pulpal origin is an inflammatory condition caused by bacterial infection. chronic infection could affect general health by increasing the production of cytokines such as interleukin-6 (il-6) that probably play a role in pathogenesis of pulpal and periapical diseases. the aim of the present study was a comparative evaluation of the level of se...

BACKGROUND To determine whether clinical examinations and periapical radiographs provide sufficient information to assess the cause of pulp and periapical diseases, the status of teeth when restored and their further treatment needs. Other aims were to determine whether restorations should be removed prior to commencing endodontic treatment, and whether the type and longevity of restorations we...

BACKGROUND/AIMS Periapical periodontitis is a common oral disease caused by bacterial invasion of the tooth pulp, which usually leads to local release of pro-inflammatory cytokines and osteolytic lesion. This study is intended to examine the effect of TNF-α on BMP9-induced osteogenic differentiation of the stem cells of dental apical papilla (SCAPs). METHODS Rat model of periapical periodonti...