OBJECTIVE To analyze the financial impact of medicine procurement with the required bioavailability and or bioequivalence tests for the basic pharmaceutical services component. METHODS A retrospective study, based on document research of competitive bidding for medicine procurement in a medium size municipality of Santa Catarina state, Southern Brazil. Bids that occurred with (2007) and witho...

In places like China, an ageing population coupled with changes in living standards and increases in disposable income, imply a shift of the demand for health-related goods and services which is likely to affect the whole organization of the industries that supply such goods and services at the global level. One of the industries most likely to be affected is the pharmaceutical sector. In the e...

BACKGROUND Bipolar I disorder (BD-I) is a chronic mental illness characterized by the presence of one or more manic episodes, or both depressive and manic episodes, usually separated by asymptomatic intervals. Pharmacists can contribute to the management of BD-I, mainly with the use of effective and safe drugs, and improve the patient's life quality through pharmaceutical care. Some studies hav...

UNLABELLED Some pharmaceutical products are capable of damaging the human auditory system. Technological progress has provided numerous resources to monitor hearing but there still is some controversy regarding the selection of the most sensitive and specific tests. OBJECTIVE to analyze audiological procedures used in the auditory monitoring of individuals exposed to ototoxic medication. ME...

The interchangeability between a generic and the respective reference drug is based on the concept of therapeutic equivalence between them, usually provided by evidence of pharmaceutical equivalence, bioequivalence, Good Manufacturing Practices (GMP), and quality control. This study aimed to evaluate the pharmaceutical equivalence between four brands of 500 mg aspirin tablets (two generic, G, a...

after the boom of pharmacological research during the 1950s, mainly as a result of the screening technique, the identification of active molecules, their reshaping by means of pharmaco-chemical drug design, and the creation of extremely efficacious and successful medicines, the pharmaceutical world sought a new source of inspiration. such biota as the tropical forest, a quantity of plants credi...

Article history: Received on: 19/10/2015 Revised on: 07/11/2015 Accepted on: 20/11/2015 Available online: 27/12/2015 The aim of this study was to describe application of molecular diagnostic tests based on nucleic acid amplification technologies (NAATs) in pharmaceutical product analysis. NAAT have become widely established in clinical microbiology laboratories in recent years, as well as in qu...

Rapid and sensitive spectrophotometric method has been developed for the determination of Enalapril in pharmaceutical formulations. The method is based on the complex formation in acidic media (pH 2), using the Tropeolin 00 and hydrochloric acid. The formed complex is extractable with dichloromethane and shows a maximum absorbance at 415 nm, following the Lambert–Beer law in the concentration r...