Two years after a quadrupled hamstring anterior cruciate ligament reconstruction using polylactic acid cross pin femoral fixation, a 32-year-old woman presented with symptoms of knee catching, locking, and stiffness. Diagnostic arthroscopy revealed a loose body in the anterior compartment of the knee which was determined to be part of the polylactic acid femoral fixation pin. The graft was inta...

Tissue engineering is an emerging field in biomedicine, holding enormous promise for regenerative medicine. Scaffolds, within which cells proliferate, are a controlling factor in tissue engineering applications. Upon fabrication, tissue scaffolds must undergo appropriate sterilization to eliminate contaminants. Current sterilization methods are either costly, time consuming, or ineffective. In ...

Novel scaffolds for vascular tissue engineering were fabricated by co-electrospinning human-like collagen/chitosan and polylactic acid at room temperature and normal pressure. By studying the effects of composition and collecting distance on the morphology of electrospun meshes, we determined that the proper collecting distance and the concentration of the solution are the keys to the success o...

Localization of a ground glass nodule is a difficult challenge for thoracic surgeons, especially for ground glass opacities (GGOs) less than 10 mm in diameter. In this study we implement a new method for preoperative localization of pulmonary (GGOs). From October 2013 to December 2014, computed tomography-guided percutaneous polylactic acid injection localizations were performed for five pulmon...

The possibility to replace damaged or diseased organs with arti®cial tissues engineered from a combination of living cells and biocompatible scaffolds is becoming a reality through multidisciplinary efforts. A number of critical components within this effort are being facilitated by microfabrication and MEMS approaches, including research tools to elucidate mechanisms which control cellular beh...

Polylactic acid (PLA) fiber, also known as corn fiber, is made of corn and other grains through fermentation, polymerization and spinning. Thus it is biodegradable and environmentally friendly. Three kinds of buffer solutions with PH values of 4, 7.2 and 11 were made for the investigation of the degradation properties of PLA. The experimental results showed that the degradation of polylactic ac...

OBJECTIVE To examine the feasibility of a new method of laryngotracheal reconstruction (LTR) that uses a bioabsorbable plating system consisting of polylactic and polyglycolic acid and provides some advantages over currently used methods. DESIGN AND INTERVENTIONS Anterior subglottic stenosis was created in 10 beagles that then underwent LTR using an autologous costochondral graft. External la...