نتایج جستجو برای: post transcriptional gene regulation
تعداد نتایج: 1884247 فیلتر نتایج به سال:
Abstract In this work, three genetic regulatory networks are considered, that model the post–transcriptional regulation of PTEN onco–suppressor gene, mediated by microRNAs and competitive endogenous RNAs, in glioblastoma multiforme, most severe brain tumours. We simulate solutions resulting stochastic differential systems discuss effects miRNA–fashioned on expression.
An increasing number of arguments, including altered microRNA expression, support the idea that post-transcriptional deregulation participates in gene disturbances found in diseased tissues. To evaluate this hypothesis, we developed a method which facilitates post-transcriptional investigations in a wide range of human cells and experimental conditions. This method, called FunREG (functional, i...
Background and purpose: LncRNAs are a group of non-coding RNAs with more than 200 nucleotides involved in transcriptional and post-transcriptional regulation of gene expression, that have a potential role in diagnosis, prevention and treatment of some disorders such as cancers. There is paucity of information about their involvement in hemophilia disease. This study aimed at discovering the rel...
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