Iatrogenic preterm premature rupture of membranes after fetoscopic procedures affects 10-47% of patients, secondary to the non-healing nature of membranes and the separation of layers during the entry. In this study we developed an in vitro model to mimic the uterine wall-fetal membrane interface using a water column with one end sealed with human fetal membranes and poultry breast, and a defec...

Fetal membranes usually rupture during the process of labor. Premature fetal membrane rupture occurs not infrequently and is associated with significant fetal and maternal morbidity. The mechanisms of normal and pathologic fetal membrane rupture are not well understood. We have examined structural and biochemical changes in the rat amnion as labor approaches in order to characterize this proces...

OBJECTIVE Bacterial colonization of the fetal membranes and its role in pathogenesis of membrane rupture is poorly understood. Prior retrospective work revealed chorion layer thinning in preterm premature rupture of membranes (PPROM) subjects. Our objective was to prospectively examine fetal membrane chorion thinning and to correlate to bacterial presence in PPROM, preterm, and term subjects. ...

Introduction: Prematurity remains the main cause of mortality and morbidity in infants and a problem in the care of pregnant women world-wide. This study describes the risk factors for having a live preterm delivery in Bandar Abbas Shariati Hospital. Methods: In this case-control study, we studied 300 neonates who were borned in Shariati hospital in 2011 and divided them into two groups: case g...

BACKGROUND: Premature Rupture of Membranes (PROM) is significantly linked to the infections-related maternal deaths. In inflammatory process, influencing stressor will stimulate activation Nuclear Factor Kappa B (NF-κB) and Receptor Advanced Gyclation End product (RAGE). Yet up date, expression NF-κB RAGE in pregnant women with PROM are still rarely studied. Therefore, this study aimed observe ...