progesterone hypersensitivity (ph) is a rare clinical condition that  displays hypersensitivity to  endogenous  or  exogenous progesterone.  it  is characterized by cyclic dermatologic manifestations at the end of the luteal phase that disappear some days after menses. we present  a  case of  24-year-old woman  showing severe angioedema attacks occurring from the first day of her menstruation a...

background and objectives: endometrial hyperplasia (eh) is an abnormal overgrowth of endometrium that may lead to endometrial cancer, especially when accompanied by atypia. the treatment of eh is challenging, and previous studies report conflicting results. metformin (dimethyl biguanide) is an anti-diabetic and insulin sensitizer agent, which is supposed to have antiproliferative and anticancer...

Abstract Background This study aimed at determining the predictive value of human chorionic gonadotropin and progesterone levels on pregnancy outcomes in patients receiving vitro fertilization due to fallopian tube associated infertility. Methods We retrospectively analyzed clinical data 854 cycles infertility fresh embryo transfer. The had been collected from January 2010 December 2018 was div...

Background & Aims: Serum progesterone level (as early as 4 weeks gestation) reflects the relation between embryo and corpus luteum. The purpose of the present study was to compare serum progesterone level on day 14 after embryo transfer among 3 groups of patients undergoing intracytoplasmic sperm injection (ICSI) cycles; normal pregnancy (viable intrauterine pregnancy), abnormal pregnancy (misc...

progesterone induced dermatitis is a rare disorder. it typically occurs in females due to an autoimmune phenomenon to endogenous progesterone production, but can also be caused by exogenous intake of a synthetic progestin. here in, we present a case of autoimmune progesterone anaphylaxis (aipa) observed in an adolescent female. the patient is an 18-year-old caucasian female with no significant ...

the brain edema is one of remarkable injuries after traumatic brain injuries (tbi). the common treatments for limiting edema are included mannitol, barbiturates, corticosteroids, hyperventilation and central nervous system derange. the most of these treatments for edema is problematic. for example, mannitol can be effective for the short period of time (24 hours) after brain injuries but is not...

traumatic brain injury (tbi) is one of the leading causes of death in men under the age of 35 that mostly occurs due to the road accidents. current clinical treatments have not enough repair and prevention of secondary damage caused by cytotoxicity. progesterone, as a primary sex hormone, acts as neuroprotection in tbi and stroke. progesterone increases anti-oxidants and decreases inflammation ...