In molecular radiotherapy with 177Lu-labeled prostate specific membrane antigen (PSMA) peptides, kidney and/or salivary glands doses limit the activity which can be administered. The aim of this work was to investigate the effect of the ligand amount and injected activity on the tumor-to-normal tissue biologically effective dose (BED) ratio for 177Lu-labeled PSMA peptides. For this retrospectiv...

1. 4,6-Dibromo-3-hydroxycarbazole (DBHC) was synthesized as an analogue of bromoeudistomin D (BED), a powerful Ca2+ releaser, and its pharmacological properties were examined. 2. In Ca2+ electrode experiments, DBHC (100 microM) markedly inhibited Ca2+ release from the heavy fraction of sarcoplasmic reticulum (HSR) induced by caffeine (1 mM) and BED (10 microM). 3. DBHC (0.1 to 100 microM) inhib...

Rhodoliths are unattached calcareous red algae that form extensive beds. Although rhodolith beds are widely distributed in temperate and tropical areas, a recent discovery in the North Pacific Ocean represents a significant northward extension of known rhodolith distribution. This bed, located in Prince William Sound, Alaska, is composed of one rhodolith species, Phymatolithon calcareum, with t...

The critical damage point of the red-bed soft rock percolation phenomenon can be described as threshold. At present, there are insufficient theoretical and experimental studies on threshold rock. In combination with analysis, compression experiment numerical simulation, destruction studied in this paper. was obtained by constructing a renormalization group model Based mechanics theory, characte...

Studies were carried out to find the influence of media and sowing conditions on field emergence Palmyrah seeds. The seeds sown in a sunken nursery bed, raised direct observe emergence. experiment was conducted Randomized Block Design with eight replications 50 each treatment. observations recorded at monthly intervals up 24 months after sowing. results revealed that bed containing red earth, s...