the influence of various polymers on the release rate of lithium carbonate from matrix-type tablets was investigated in an attempt to formulate a sustained release solid dosage form. for this purpose, tablets containing 450 mg of lithium carbonate along with various amounts of carbopol 934p, 971p, 974p, pemulen and eudragit rlpo as retarding agents and inactive ingredients (e.g. pvp, avicel or ...

Microencapsulation has become a common technique in the production of controlled release dosage forms. Many results have been reported, concerning the use of alginate beads as controlled release drug formulations. Alginate has a unique gel-forming property in the presence of multivalent cations, in an aqueous medium. Ibuprofen is an excellent analgesic and antipyretic, non-steroidal anti-inflam...

microencapsulation has become a common technique in the production of controlled release dosage forms. many results have been reported, concerning the use of alginate beads as controlled release drug formulations. alginate has a unique gel-forming property in the presence of multivalent cations, in an aqueous medium. ibuprofen is an excellent analgesic and antipyretic, non-steroidal anti-inflam...

Hydrophobic grade fumed silicas are generally used in tabletting as lubricants. They are also found to retard the release of pharmaceutical actives. This is because of their hydrophobic nature, which gives good cohesive and adhesive properties. considering this point it was thought that they could be used as dry coating agents for solid dosages forms. The model drug selected for this work was p...

Specific delivery of therapeutic agents to solid tumors and their bioavailability at the target site are the most clinically important and challenging goals in cancer therapy. Liposomes are promising nanocarriers and have been well investigated for cancer therapy. In spite of preferred accumulation in tumors via the enhanced permeability and retention (EPR) effect, inefficient drug release at t...

Nano-structured surface and its ability to dual release of osteogenic and anti-inflammatory agents have a positive effect on the success of using titanium in orthopedic applications. For this purpose, TiO2 nanotubes (TNTs) were created via anodization method on Ti sheets and loaded by β-glycerophosphate (GP) and dexamethasone (DEX) as osteogenic and anti-inflammatory agents, respecti...