OBJECTIVE This paper describes recent advances in the neurobiology of mental retardation, emphasizing new diagnostic resources provided by cytogenetics, molecular testing, and neuroimaging. SOURCES OF DATA MEDLINE (January 2000 through October 2003), using the following key words: mental retardation, developmental disability, child, and adolescent. Search of the Pediatrics and New England Jou...

A color-digit interference task and two sorting tasks were devised as variants of the Stroop Color-Word Test and Gardner's Sorting Tasks, respectively. These tasks proved applicable to a mentally retarded sample and provided reliable measures of two cognitive control dimensions (constricted-flexible control and equivalence range). As predicted, the main test scores were significantly more varia...

Most of the autistic disorder patients are also mentally retarded and many mentally retarded persons exhibit autistic symptoms. By using a standard instrument (Ritvo-Freeman Real Life Rating Scale) the autistic features of the mentally retarded children were studied. The study also examined the influence of age, sex and level of mental retardation on the occurrence of autistic symptoms. Childre...

background and purpose: birth of a mentally retarded child is a significant challenge in every family and is associated with the possibility of parental stress and depression. this study aimed to evaluate the self-concept of mothers with educable mentally retarded (emr) children. methods: this cross-sectional study was conducted on 40 mothers with emr children in the only special primary school...

Service facilities for persons with severe mental retardation and multiple disabilities are meagre. The present study aims at analysing the problems of persons with severe mental retardation and multiple disabilities in terms of presenting complaints, previous consultations, aetiological factors and associated problems. Persons with severe mental retardation and multiple disabilities numbering ...

The 5' untranslated CGG repeat in the fragile X mental retardation-1 (FMR1) gene is expanded in families with fragile X syndrome, with more than 200 CGGs resulting in mental retardation due to the absence of the encoded fragile X mental retardation protein (FMRP). Intermediate and premutation alleles, containing between approximately 40 and 200 repeats, express grossly normal FMRP levels and su...

Introduction: Intellectual disability or intellectual retardation is a condition in which total mental functioning is distinctively below average and there are disabilities in adaptive behaviors during growth. According to the definition of American Mental Disability Community in 1992 a person is considered intellectually disabled if he or she has an IQ (intelligence quotient) of less than 70...