There isn’t a consensus to the treatment of varicose veins because we don’t have randomized controlled trials [1]. Indication to the treatment is based on different criteria: etiological, clinical and diagnostic. The treatments include: conservative therapy, sclerotherapy, phlebectomy, endovenous laser therapy, radiofrequency ablation, and surgery involving saphenous ligation and stripping [2]....

Objectives This study assessed the effectiveness and patient experience of the ClariVein® endovenous occlusion catheter for varicose veins from a large single-centre series in the UK. Methods A total of 300 patients (371 legs) underwent ClariVein® treatment for their varicose veins; 184 for great saphenous vein (GSV) incompetence, 62 bilateral GSV, 23 short saphenous vein (SSV), 6 bilateral SSV...

OBJECTIVE Long-term durability of saphenous vein grafts used for coronary artery bypass grafting is limited by neointimal formation. Arterial vascular injury is known to activate intracellular mitogen-activated protein kinases, including extracellular signal-regulated kinases and c-jun N-terminal kinases, that affect cell differentiation, proliferation, migration, and apoptosis. This study test...

Aims: Extracellular matrix remodeling has been implicated in a number of vascular conditions, including venous hypertension and varicose veins. However, to date no systematic analysis of matrix remodeling in human veins has been performed. Methods and Results: To understand the consequences of venous hypertension, normal and varicose veins were evaluated using proteomics approaches targeting th...

Although the baboon is considered a good animal model in biomedical research, no description of the superficial veins of the foot in Papio anubis is found in the available literature. The current study was conducted to document the anatomy of these veins in the baboon foot. A macroscopic anatomical investigation was carried out on 20 hind legs (10 cadavers) of the adult Papio anubis (9 males an...

The saphenous venous system was visualized by CT without any contrast medium injection. Volumetric data were acquired with a multidetector spiral CT (Siemens, Somatom Plus 4 Volume Zoom) with the following parameters: collimation, 1 mm; pitch, 4; reconstruction, 1.2 mm. Reformatted images were then transferred in DICOM format to an 02 work station (Silicon Graphics) and postprocessed by the sof...

External valvuloplasty has been gaining in popularity as an alternative treatment for incompetent great saphenous veins. The procedure involves the implantation of a synthetic cuff around the saphenofemoral junction to compress the vein to a physiological diameter and thus restore the competence of the terminal and preterminal veins (1) (▶ Fig. 1). The important advantage of this method is that...

VANHOUTTE, PAUL M., AND ROBERT R. LORENZ. E$ect of temperature on reactivity of saphenous, mesenteric, and femoral veins of the dog. Am. J. Physiol. 218(6) : 1746-l 750. 1970.-The contraction of cutaneous veins of the dog caused by sympathetic nerve stimulation or by vasoactive drugs has been found previously to be potentiated by cooling and depressed by warming. To determine if this effect was...

VANHOUTTE, PAUL M., AND ROBERT R. LORENZ. E$ect of temperature on reactivity of saphenous, mesenteric, and femoral veins of the dog. Am. J. Physiol. 218(6) : 1746-l 750. 1970.-The contraction of cutaneous veins of the dog caused by sympathetic nerve stimulation or by vasoactive drugs has been found previously to be potentiated by cooling and depressed by warming. To determine if this effect was...

Overview Varicose veins of the lower extremities are found in the superficial venous system which includes the great saphenous vein (GSV) and the small saphenous vein (SSV), and their tributaries. One-way valves are present in the superficial venous system. These valves prevent backward flow of blood within the vein (reflux) and keep the blood moving toward the heart. The condition of improperl...