introduction: studies with single photon emission computed tomography (spect) have revealed inconsistent changes of regional cerebral blood flow (rcbf) in schizophrenia. some studies investigated the rcbf and its relationship with psychopathology, positive and negative symptoms in treated patients. however, there is a little information about the pattern of rcbf in recently untreated or never t...

objective: despite the discovery of new antipsychotic drugs in recent years, a number of schizophrenic patients show no response to such drugs and are considered treatment-resistant. in such cases, clozapine and occasionally ect or a combination of drugs are used, though they are not very effective. in recent years, the combination of clozapine and ect for treatment-resistant schizophrenic pati...

Introduction: Previous studies have reported contradicting results about the effect of medication therapy on attribution bias and jumping to conclusion (JTC) bias in schizophrenic patients. This study aims at analyzing the effect of medication on attribution bias and JTC bias in schizophrenic patients. Methods: This study is an ex post facto and casual-comparative research. 28 people includi...

objectives: one of the principle of mental health programs is burden and coping of caregivers of chronically mental disorders patients. in this regard, the aim of present study was to measure the amount of burden and relationship between burden and their coping strategies of caregivers. methods: one hundred of main caregivers of patients (50 schizophrenic patients, 50 bipolar patients) from bot...

objective: the present study aimed to clarify dissociative symptoms in patients with schizophrenia and its association with negative and positive symptom of schizophrenia. methods: based on the 4th edition of diagnostic and statistical manual of mental disorders (dsm-iv) criteria, 80 schizophrenic subjects were randomly selected from patients who referred to the clinics of psychiatry hospital i...

Recently, extensive efforts have been made to understand the rate of energy expenditure and the weight gain associated with atypical antipsychotic treatment, including identification of markers of obesity risk. In recent years, leptin, an adipocyte hormone, has gained significant interest in psychiatric disorders. S100B has been considered as a surrogate marker for astrocyte-specific damage in ...

anxiety is one of the symptoms in chronic schizophrenic patients. past research studies show that psychodrama as a group therapy is effective in treatment and rehabilitation of psychological disorders. the aim of this study is to explore the effect of psychodrama on the reduction of anxiety in schizophrenic patients. 26 male hospitalized chronic schizophrenic patients were randomly assigned int...